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U 18666A

Tocris Bioscience a Bio-Techne Brand

Hedgehog Signaling Inhibitors Small Molecule
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Key Product Details

Description: Inhibitor of Hedgehog (Hh) signaling. Also inhibits cholesterol synthesis
Chemical Name: (3β)-3-[2-(Diethylamino)ethoxy]androst-5-en-17-one hydrochloride
Molecular Weight: 424.07

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Citations for U 18666A


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  • Cholesterol accumulation increased by U18666A treatment
    Name: ASHUTOSH SINGHAL
    Species: Human
    Assay Type: In Vitro
    Cell Line/Tissue: HeLa
    I used 2.5-10 ug/ml of U18666A to inhibit the cholesterol efflux in HeLa cells and it worked perfectly as I observed in U18666A treated HeLa cells accumulated cholesterol significantly. I used Filipin staining to image and quantitate the cholesterol levels.
    I dissolved the U18666A in water and stored at -20C in aliquots.

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Product Documents for U 18666A

Certificate of Analysis

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