Tyrphostin B44, (+) enantiomer

Name: Tyrphostin B44, (+) enantiomer
Brand: Tocris Bioscience
SKU: 0579

Tocris Bioscience, part of Bio-Techne | Catalog # 0579

COA / SDS

EGFR-kinase inhibitor

Discontinued Product

0579 has been discontinued. View all EGF Receptor Inhibitors products.

Key Product Details

Description:	EGFR-kinase inhibitor
Chemical Name:	(S)-(E)-2-Cyano-3-(3',4'-dihydroxyphenyl)-N-(1-phenylethyl)-2-propenamide
Molecular Weight:	308.34

View Full Technical Details for Tyrphostin B44, (+) enantiomer

Technical Data
Citations

Biological Activity for Tyrphostin B44, (+) enantiomer

Tyrphostin B44, (+) enantiomer is an epidermal growth factor receptor (EGFR) kinase inhibitor (IC₅₀ = 0.86 μM). Slightly less active than the (-) enantiomer.

(-)-enantiomer also available.

Technical Data for Tyrphostin B44, (+) enantiomer

M. Wt	308.34
Formula	C₁₈H₁₆N₂O₃
Storage	Desiccate at +4°C
CAS Number	133550-37-5
PubChem ID	5328769
InChi Key	UMGQVUWXNOJOSJ-DGGAMASNSA-N
Smiles	OC1=C(O)C=CC(\C=C(C(N[C@@H](C)C2=CC=CC=C2)=O)/C#N)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for Tyrphostin B44, (+) enantiomer

References are publications that support the biological activity of the product.

Gazit Tyrphostins. 2. Heterocyclic and α-substituted benzylidenemalononitrile tyrophostins as potent inhibitors of EGF receptor and ErbB2/neu tyrosine kinases. J.Med.Chem. 1991 PMID: 1676428

Tyrphostin B44, (+) enantiomer

Tocris Bioscience, part of Bio-Techne | Catalog # 0579

Key Product Details

Biological Activity for Tyrphostin B44, (+) enantiomer

Technical Data for Tyrphostin B44, (+) enantiomer

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for Tyrphostin B44, (+) enantiomer

Product Documents for Tyrphostin B44, (+) enantiomer

COA

Certificate of Analysis

SDS

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