Tropicamide

Name: Tropicamide
Brand: Tocris Bioscience
SKU: 0909

Tocris Bioscience a Bio-Techne Brand

Catalog # 0909

Citations (1)

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Key Product Details

Description:	Selective M₄ antagonist
Chemical Name:	N-Ethyl-3-hydroxy-2-phenyl-N-(pyridinylmethyl)propanamide
Purity:	≥98% (HPLC)
Molecular Weight:	284.36

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Biological Activity for Tropicamide

Tropicamide is an M₄ selective muscarinic receptor antagonist.

Compound Libraries for Tropicamide

Tropicamide is also offered as part of the Tocriscreen 2.0 Max and Tocriscreen FDA-Approved Drugs. Find out more about compound libraries available from Tocris.

Technical Data for Tropicamide

M. Wt	284.36
Formula	C₁₇H₂₀N₂O₂
Storage	Store at RT
Purity	≥98% (HPLC)
CAS Number	1508-75-4
PubChem ID	5593
InChi Key	BGDKAVGWHJFAGW-UHFFFAOYSA-N
Smiles	CCN(CC1=CC=NC=C1)C(=O)C(CO)C1=CC=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Tropicamide

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO		100

Preparing Stock Solutions for Tropicamide

The following data is based on the product molecular weight 284.36.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.52 mL	17.58 mL	35.17 mL
5 mM	0.70 mL	3.52 mL	7.03 mL
10 mM	0.35 mL	1.76 mL	3.52 mL
50 mM	0.07 mL	0.35 mL	0.70 mL

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Reconstitution Calculator

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References for Tropicamide

References are publications that support the biological activity of the product.

Hernandez Different muscarinic receptor subtypes mediating the phasic activity and basal tone of pig isolated intravesical ureter. Br.J.Pharmacol. 1993 PMID: 7905771
Lazareno Characterisation of muscarinic M₄ binding sites in rabbit lung, chicken heart and NG 108-15 cells. Mol.Pharmacol. 1990 PMID: 2250662

Citations for Tropicamide (1)

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Citations are publications that use Bio-Techne products. Selected citations for Tropicamide include:

Sallo et al. (2012) The IS/OS junction layer in the natural history of type 2 idiopathic macular telangiectasia. Invest Ophthalmol Vis Sci. 53:7889
PMID: 23092925

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Product Documents for Tropicamide

COA

Certificate of Analysis

To download a Certificate of Analysis, please select a batch below.