trans-4-Hydroxycrotonic acid

Name: trans -4-Hydroxycrotonic acid
Brand: Tocris Bioscience
SKU: 0538

Tocris Bioscience, part of Bio-Techne | Catalog # 0538

COA / SDS

GHB receptor ligand

Discontinued Product

0538 has been discontinued. View all Additional GABA Compounds products.

Key Product Details

Description:	GHB receptor ligand
Chemical Name:	trans-4-Hydroxy-2-butenoic acid
Purity:	≥99% (HPLC)
Molecular Weight:	102.09

View Full Technical Details for trans-4-Hydroxycrotonic acid

Technical Data
Citations

Biological Activity for trans-4-Hydroxycrotonic acid

Binds to the γ-hydroxybutyric acid (GHB) receptor with higher affinity than GHB itself. May be an endogenous ligand.

Technical Data for trans-4-Hydroxycrotonic acid

M. Wt	102.09
Formula	C₄H₆O₃
Storage	Desiccate at +4°C
Purity	≥99% (HPLC)
CAS Number	24587-49-3
PubChem ID	6155526
InChi Key	RMQJECWPWQIIPW-OWOJBTEDSA-N
Smiles	OC\C=C\C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for trans-4-Hydroxycrotonic acid

References are publications that support the biological activity of the product.

Hechler Gamma hydroxybutyrate ligands posses antiDArgic and neuroleptic-like activities. J.Pharmacol.Exp.Ther. 1993 PMID: 8095552
Vayer Natural occurrence of trans-gamma hydroxycrotonic acid in rat brain. Biochem.Pharmacol. 1985 PMID: 4015683
Bourguignon Analogues of γ-hydroxybutyric acid. Synthesis and binding studies. J.Med.Chem. 1988 PMID: 3361576

trans-4-Hydroxycrotonic acid

Tocris Bioscience, part of Bio-Techne | Catalog # 0538

Key Product Details

Biological Activity for trans-4-Hydroxycrotonic acid

Technical Data for trans-4-Hydroxycrotonic acid

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for trans-4-Hydroxycrotonic acid

Product Documents for trans-4-Hydroxycrotonic acid

COA

Certificate of Analysis

SDS

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