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Bio-Techne Corporation
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Key Product Details
| Description: | Bioactive compound library for high-throughput screening, high-content screening and chemical biology applications; comprised of 1280 compounds (50 μL 10 mM DMSO solutions) |
| Key Format Details: |
 The Tocriscreen 2.0 Compound Library contains bioactive compounds covering a diverse range of molecular targets; 7-TM receptors (GPCRs; 27%), non-kinase enzymes (21%), kinases including enzyme-linked receptors (20%), ion channels (13%), cell biology targets (9%), nuclear receptors (6%), and transporters and other pharmacological targets (5%). |
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Citations (7)
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Citations are publications that use Bio-Techne products. Selected citations for Tocriscreen 2.0 Mini include:
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Sowa et al.
(2020)
A FRET-based high-throughput screening platform for the discovery of chemical probes targeting the scaffolding functions of human tankyrases.
Sci Rep.
10:12357
PMID: 32704068 -
Seki et al.
(2020)
Induced pluripotent stem cell-derived monocytic cell lines from a NOMID patient serve as a screening platform for modulating NLRP3 inflammasome activity.
PLoS One.
15:e0237030
PMID: 32810141 -
Sartori et al.
(2019)
BIN1 recovers tauopathy-induced long-term memory deficits in mice and interacts with Tau through Thr348 phosphorylation.
Acta Neuropathol.
138:631
PMID: 31065832 -
Trogden et al.
(2018)
An image-based small-molecule screen identifies vimentin as a pharmacologically relevant target of SimV. in cancer cells.
FASEB J.
32:2841
PMID: 29401610 -
Paul et al.
(2017)
Hypothalamic regulation of regionally distinct adult neural stem cells and neurogenesis.
Science.
356:1383
PMID: 28619719 -
Hermanson et al.
(2012)
Screening for novel LRRK2 inhibitors using a high-throughput TR-FRET cellular assay for LRRK2 Ser935 phosphorylation.
PLoS One.
7:e43580
PMID: 22952710 -
Fujita et al.
(2011)
A GPR40 agonist GW9508 suppresses CCL5, CCL17, and CXCL10 induction in keratinocytes and attenuates cutaneous immune inflammation.
J Invest Dermatol.
131:1660
PMID: 21593768
There are no citations that match your criteria.
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