Key Product Details
Description: | Bioactive compound library for high-throughput screening, high-content screening and chemical biology applications; comprised of 1280 compounds (50 μL 10 mM DMSO solutions) |
Key Format Details: |
![]() The Tocriscreen 2.0 Compound Library contains bioactive compounds covering a diverse range of molecular targets; 7-TM receptors (GPCRs; 27%), non-kinase enzymes (21%), kinases including enzyme-linked receptors (20%), ion channels (13%), cell biology targets (9%), nuclear receptors (6%), and transporters and other pharmacological targets (5%). |
Customers also Viewed
Citations for Tocriscreen 2.0 Mini (15)
Citations are publications that use Bio-Techne products. Selected citations for Tocriscreen 2.0 Mini include:
-
Gull et al.
(2022)
Screening of chemical libraries using xenopus embryos and tadpoles for phenotypic drug discovery.
Cold Spring Harb.Protoc..
2022;
PMID: 36180216 -
Hühn et al.
(2022)
Prolonged estrogen deprivation triggers a broad immunosuppressive phenotype in breast cancer cells.
Mol Oncol.
16:148
PMID: 34392603 -
Kato et al.
(2021)
Antiviral activity of CD437 against mumps virus.
Front.Microbiol..
12:751909
PMID: 34867872 -
Corman et al.
(2021)
A chemical screen for modulators of mRNA translation identifies a distinct mechanism of toxicity for sphingosine kinase inhibitors
PLoS Biol.
2021;
PMID: 34033645 -
Seki et al.
(2020)
Induced pluripotent stem cell-derived monocytic cell lines from a NOMID patient serve as a screening platform for modulating NLRP3 inflammasome activity.
PLoS One.
15:e0237030
PMID: 32810141 -
Sowa et al.
(2020)
A FRET-based high-throughput screening platform for the discovery of chemical probes targeting the scaffolding functions of human tankyrases.
Sci Rep.
10:12357
PMID: 32704068 -
Xiao et al.
(2020)
HIV-1 fusion inhibitors targeting the membrane-proximal external region of Env spikes.
Nat.Chem.Biol..
16:529
PMID: 32152540 -
Sartori et al.
(2019)
BIN1 recovers tauopathy-induced long-term memory deficits in mice and interacts with Tau through Thr348 phosphorylation.
Acta Neuropathol.
138:631
PMID: 31065832 -
Kato et al.
(2019)
Identification of inhibitors of dengue viral replication using replicon cells expressing secretory luciferase.
Antiviral.Res..
172:104643
PMID: 31678478 -
Corman et al.
(2019)
A Chemical Screen Identifies Compounds Limiting the Toxicity of C9ORF72 Dipeptide Repeats
Cell Chem Biol.
26:235
PMID: 30527999 -
Trogden et al.
(2018)
An image-based small-molecule screen identifies vimentin as a pharmacologically relevant target of SimV. in cancer cells.
FASEB J.
32:2841
PMID: 29401610 -
Paul et al.
(2017)
Hypothalamic regulation of regionally distinct adult neural stem cells and neurogenesis.
Science.
356:1383
PMID: 28619719 -
Jing et al.
(2017)
A small-molecule screen reveals that HSP90� promotes the conversion of induced pluripotent stem cell-derived endoderm to a hepatic fate and regulates HNF4A turnover.
Development.
144:1764
PMID: 28360131 -
Hermanson et al.
(2012)
Screening for novel LRRK2 inhibitors using a high-throughput TR-FRET cellular assay for LRRK2 Ser935 phosphorylation.
PLoS One.
7:e43580
PMID: 22952710 -
Fujita et al.
(2011)
A GPR40 agonist GW9508 suppresses CCL5, CCL17, and CXCL10 induction in keratinocytes and attenuates cutaneous immune inflammation.
J Invest Dermatol.
131:1660
PMID: 21593768
There are no citations that match your criteria.