Tocriscreen 2.0 Mini
Tocris Bioscience a Bio-Techne Brand
Key Product Details
|Description:||Bioactive compound library for high-throughput screening, high-content screening and chemical biology applications; comprised of 1280 compounds (50 μL 10 mM DMSO solutions)|
|Key Format Details:||
The Tocriscreen 2.0 Compound Library contains bioactive compounds covering a diverse range of molecular targets; 7-TM receptors (GPCRs; 27%), non-kinase enzymes (21%), kinases including enzyme-linked receptors (20%), ion channels (13%), cell biology targets (9%), nuclear receptors (6%), and transporters and other pharmacological targets (5%).
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Citations for Tocriscreen 2.0 Mini (15)
Citations are publications that use Bio-Techne products. Selected citations for Tocriscreen 2.0 Mini include:
Gull et al.
Screening of chemical libraries using xenopus embryos and tadpoles for phenotypic drug discovery.
Cold Spring Harb.Protoc..
Hühn et al.
Prolonged estrogen deprivation triggers a broad immunosuppressive phenotype in breast cancer cells.
Kato et al.
Antiviral activity of CD437 against mumps virus.
Corman et al.
A chemical screen for modulators of mRNA translation identifies a distinct mechanism of toxicity for sphingosine kinase inhibitors
Seki et al.
Induced pluripotent stem cell-derived monocytic cell lines from a NOMID patient serve as a screening platform for modulating NLRP3 inflammasome activity.
Sowa et al.
A FRET-based high-throughput screening platform for the discovery of chemical probes targeting the scaffolding functions of human tankyrases.
Xiao et al.
HIV-1 fusion inhibitors targeting the membrane-proximal external region of Env spikes.
Sartori et al.
BIN1 recovers tauopathy-induced long-term memory deficits in mice and interacts with Tau through Thr348 phosphorylation.
Kato et al.
Identification of inhibitors of dengue viral replication using replicon cells expressing secretory luciferase.
Corman et al.
A Chemical Screen Identifies Compounds Limiting the Toxicity of C9ORF72 Dipeptide Repeats
Cell Chem Biol.
Trogden et al.
An image-based small-molecule screen identifies vimentin as a pharmacologically relevant target of SimV. in cancer cells.
Paul et al.
Hypothalamic regulation of regionally distinct adult neural stem cells and neurogenesis.
Jing et al.
A small-molecule screen reveals that HSP90� promotes the conversion of induced pluripotent stem cell-derived endoderm to a hepatic fate and regulates HNF4A turnover.
Hermanson et al.
Screening for novel LRRK2 inhibitors using a high-throughput TR-FRET cellular assay for LRRK2 Ser935 phosphorylation.
Fujita et al.
A GPR40 agonist GW9508 suppresses CCL5, CCL17, and CXCL10 induction in keratinocytes and attenuates cutaneous immune inflammation.
J Invest Dermatol.
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