Tocriscreen 2.0 Mini

Name: Tocriscreen 2.0 Mini
Brand: Tocris Bioscience
SKU: 7151
Price: 9062 USD

Tocris Bioscience a Bio-Techne Brand

Catalog # 7151

Citations (15)

COA / SDS

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Key Product Details

Description:

Bioactive compound library for high-throughput screening, high-content screening and chemical biology applications; comprised of 1280 compounds (50 μL 10 mM DMSO solutions)

Key Format Details:

96-well racks with Matrix storage tubes & SepraSeal caps
Compounds arranged 80 per rack with 16 racks per library
Pre-dissolved in DMSO

Many compounds are exclusive to Tocris
Unique library with low overlap
Full chemical and biological data available
Exceptional purity

Target Classes Covered by the Tocriscreen 2.0 Compound Library

The Tocriscreen 2.0 Compound Library contains bioactive compounds covering a diverse range of molecular targets; 7-TM receptors (GPCRs; 27%), non-kinase enzymes (21%), kinases including enzyme-linked receptors (20%), ion channels (13%), cell biology targets (9%), nuclear receptors (6%), and transporters and other pharmacological targets (5%).

View Full Technical Details for Tocriscreen 2.0 Mini

Product Description for Tocriscreen 2.0 Mini

Tocriscreen 2.0 Mini is a library of 1280 biologically active compounds from the Tocris catalog. Covers a wide range of pharmacological targets and research areas. Compounds are supplied pre-dissolved in 50 μL 10 mM DMSO solutions.

This library replaces the Tocriscreen Plus Mini (Cat. No. 5841).

For more information on the Tocriscreen 2.0 Compound Libraries, please download our informative flyer.

If this library does not suit your needs, please submit your requirements through our Tocriscreen PRO custom compound library service.

Request Compound List

A list of the compounds available in the Tocriscreen 2.0 Mini can be requested in Excel or SD format via our Tocriscreen & Custom Library Inquiries form.

Technical Data for Tocriscreen 2.0 Mini

Storage	Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References for Tocriscreen 2.0 Mini

References are publications that support the biological activity of the product.

Li Small-molecule-driven direct reprogramming of mouse fibroblasts into functional neurons. Cell Stem Cell. 2015 PMID: 26253201
Yu Small molecules enhance CRISPR genome editing in pluripotent stem cells. Cell Stem Cell. 2015 PMID: 25658371
Li Generation of iPSCs from mouse fibroblasts with a single gene, Oct4, and small molecules. Cell Research. 2011 PMID: 20956998
Beacham Cell-based potassium ion channel screening using the FluxOR^TM assay. J.Biomol.Screens. 2010 PMID: 20208034
Hattori Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis. Proc.Natl.Acad.Sci.USA. 2010 PMID: 20142487

Citations for Tocriscreen 2.0 Mini (15)

Showing 1 - 10 of 15 citations Showing All

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Citations are publications that use Bio-Techne products. Selected citations for Tocriscreen 2.0 Mini include:

Gull et al. (2022) Screening of chemical libraries using xenopus embryos and tadpoles for phenotypic drug discovery. Cold Spring Harb.Protoc.. 2022;
PMID: 36180216
Hühn et al. (2022) Prolonged estrogen deprivation triggers a broad immunosuppressive phenotype in breast cancer cells. Mol Oncol. 16:148
PMID: 34392603
Kato et al. (2021) Antiviral activity of CD437 against mumps virus. Front.Microbiol.. 12:751909
PMID: 34867872
Corman et al. (2021) A chemical screen for modulators of mRNA translation identifies a distinct mechanism of toxicity for sphingosine kinase inhibitors PLoS Biol. 2021;
PMID: 34033645
Seki et al. (2020) Induced pluripotent stem cell-derived monocytic cell lines from a NOMID patient serve as a screening platform for modulating NLRP3 inflammasome activity. PLoS One. 15:e0237030
PMID: 32810141
Sowa et al. (2020) A FRET-based high-throughput screening platform for the discovery of chemical probes targeting the scaffolding functions of human tankyrases. Sci Rep. 10:12357
PMID: 32704068
Xiao et al. (2020) HIV-1 fusion inhibitors targeting the membrane-proximal external region of Env spikes. Nat.Chem.Biol.. 16:529
PMID: 32152540
Sartori et al. (2019) BIN1 recovers tauopathy-induced long-term memory deficits in mice and interacts with Tau through Thr³⁴⁸ phosphorylation. Acta Neuropathol. 138:631
PMID: 31065832
Kato et al. (2019) Identification of inhibitors of dengue viral replication using replicon cells expressing secretory luciferase. Antiviral.Res.. 172:104643
PMID: 31678478
Corman et al. (2019) A Chemical Screen Identifies Compounds Limiting the Toxicity of C9ORF72 Dipeptide Repeats Cell Chem Biol. 26:235
PMID: 30527999
Trogden et al. (2018) An image-based small-molecule screen identifies vimentin as a pharmacologically relevant target of SimV. in cancer cells. FASEB J. 32:2841
PMID: 29401610
Paul et al. (2017) Hypothalamic regulation of regionally distinct adult neural stem cells and neurogenesis. Science. 356:1383
PMID: 28619719
Jing et al. (2017) A small-molecule screen reveals that HSP90� promotes the conversion of induced pluripotent stem cell-derived endoderm to a hepatic fate and regulates HNF4A turnover. Development. 144:1764
PMID: 28360131
Hermanson et al. (2012) Screening for novel LRRK2 inhibitors using a high-throughput TR-FRET cellular assay for LRRK2 Ser935 phosphorylation. PLoS One. 7:e43580
PMID: 22952710
Fujita et al. (2011) A GPR40 agonist GW9508 suppresses CCL5, CCL17, and CXCL10 induction in keratinocytes and attenuates cutaneous immune inflammation. J Invest Dermatol. 131:1660
PMID: 21593768

There are no citations that match your criteria.

Showing 1 - 10 of 15 citations Showing All

Product Documents for Tocriscreen 2.0 Mini

COA

Certificate of Analysis is currently unavailable on-line. Please contact Customer Service.