TCS 3035
Tocris Bioscience, part of Bio-Techne | Catalog # 4244
GPR35 agonist
Discontinued Product
4244 has been discontinued.
View all GPR35 Agonists products.
Product Description
TCS 3035 is a GPR35 agonist (pEC50 values are 5.13 and 5.86 for rat and human GPR35 orthologs, respectively).Product Specifications
Molecular Weight
279.27
Formula
C12H9NO5S
Storage
Store at +4°C
Purity
≥98% (HPLC)
Chemical Name
2-[4-[(Z)-(2,4-Dioxo-5-thiazolidinylidene)methyl]phenoxyacetic acid
CAS Number
871085-49-3
PubChem ID
2295463
InChI Key
WXMCOLGPDOYHNK-UITAMQMPSA-N
SMILES
O=C(/C(S2)=C/C1=CC=C(OCC(O)=O)C=C1)NC2=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 27.93 | 100 |
Preparing Stock Solutions
for TCS 3035
The following data is based on the product molecular weight 279.27
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.58 mL | 17.90 mL | 35.81 mL |
| 5 mM | 0.72 mL | 3.58 mL | 7.16 mL |
| 10 mM | 0.36 mL | 1.79 mL | 3.58 mL |
| 50 mM | 0.07 mL | 0.36 mL | 0.72 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Jenkins Agonist activation of the G protein-coupled receptor GPR35 involves transmembrane domain III and is transduced via Gα13 and β-arrestin-2. Br.J.Pharmacol. 2011 PMID: 20958291
Product Specific Notices for TCS 3035
For research use only
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