TCS 1205

Tocris Bioscience, part of Bio-Techne | Catalog # 3941

GABAA agonist; displays subtype selectivity
Discontinued Product
3941 has been discontinued. View all GABA-A Receptor Agonists products.

Key Product Details

Description

GABAA agonist; displays subtype selectivity

View all GABA-A Receptor Agonists »

Product Description

GABAA α2 agonist and GABAA α1 partial agonist in vitro (Ki values are 14 and 121 nM respectively). Exhibits non-sedative anxiolytic activity in vivo.

Product Specifications

Molecular Weight

337.33

Formula

C18H15N3O4

Storage

Store at RT

Purity

≥99% (HPLC)

Chemical Name

5-Nitro-α-oxo-N-(1R)-phenylethyl]-1H-indole-3-acetamide

CAS Number

355022-97-8

PubChem ID

10315001

InChI Key

VCKKJKQZHHPPDR-LLVKDONJSA-N

SMILES

O=C(C(N[C@H](C)C3=CC=CC=C3)=O)C2=CNC1=CC=C([N+]([O-])=O)C=C12

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 33.73 100

Preparing Stock Solutions for TCS 1205

The following data is based on the product molecular weight 337.33

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.96 mL 14.82 mL 29.64 mL
5 mM 0.59 mL 2.96 mL 5.93 mL
10 mM 0.30 mL 1.48 mL 2.96 mL
50 mM 0.06 mL 0.30 mL 0.59 mL

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

x
=
x

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Product Documents for TCS 1205

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for TCS 1205

For research use only

Privacy Policy
Cookie Policy
Site Map
© Copyright 2026 Bio-Techne. All Rights Reserved. All trademarks and registered trademarks are the property of Bio-Techne and its brands unless otherwise specified.