TCN 213

Tocris Bioscience, part of Bio-Techne | Catalog # 4163

NMDA antagonist; selective for GluN2A over GluN2B containing receptors
Discontinued Product
4163 has been discontinued. View all NMDA Receptor Antagonists products.

Key Product Details

Description

NMDA antagonist; selective for GluN2A over GluN2B containing receptors

View all NMDA Receptor Antagonists »

Product Description

TCN 213 is a NMDA receptor antagonist, selective for GluN1/GluN2A (formally NR1/NR2A) (pIC50 = 5.4) over GluN1/GluN2B (formally NR1/NR2B) containing receptors.

Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions.

Product Specifications

Molecular Weight

376.54

Formula

C18H24N4OS2

Storage

Store at +4°C

Purity

≥99% (HPLC)

Chemical Name

N-(Cyclohexylmethyl)-2-[(5-[(phenylmethyl)amino]-1,3,4-thiadiazol-2-yl}thio]acetamide

CAS Number

556803-08-8

PubChem ID

2608149

InChI Key

XBAZPYFIYYCZBO-UHFFFAOYSA-N

SMILES

O=C(NCC2CCCCC2)CSC1=NN=C(NCC3=CC=CC=C3)S1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 28.24 75
Ethanol 3.77 10

Preparing Stock Solutions for TCN 213

The following data is based on the product molecular weight 376.54

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.75 mM 3.54 mL 17.71 mL 35.41 mL
3.75 mM 0.71 mL 3.54 mL 7.08 mL
7.5 mM 0.35 mL 1.77 mL 3.54 mL
37.5 mM 0.07 mL 0.35 mL 0.71 mL

Calculators

Molarity Calculator

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for TCN 213

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for TCN 213

For research use only

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