Talsupram hydrochloride

Name: Talsupram hydrochloride
Brand: Tocris Bioscience
SKU: 4352

Tocris Bioscience, part of Bio-Techne | Catalog # 4352

COA / SDS

Selective inhibitor of noradrenalin transporters

Discontinued Product

4352 has been discontinued. View all Adrenergic Transporter Inhibitors products.

Key Product Details

Description:	Selective inhibitor of noradrenalin transporters
Chemical Name:	1,3-Dihydro-N,3,3-trimethyl-1-phenylbenzo[c]thiophene-1-propanamine hydrochloride
Purity:	≥98% (HPLC)
Molecular Weight:	347.95

View Full Technical Details for Talsupram hydrochloride

Technical Data
Citations

Biological Activity for Talsupram hydrochloride

Talsupram hydrochloride is a selective noradrenalin re-uptake inhibitor; exhibits a high affinity for the human noradrenalin transporter (NET) against SERT and DAT (IC₅₀ values are 0.79, 850 and 9300 nM for inhibition of monoamine uptake by NET, SERT and DAT respectively). Antidepressant.

Technical Data for Talsupram hydrochloride

M. Wt	347.95
Formula	C₂₀H₂₅NS.HCl
Storage	Desiccate at RT
Purity	≥98% (HPLC)
CAS Number	25487-28-9
PubChem ID	33013
InChi Key	YMZCMCDSCRSIBS-UHFFFAOYSA-N
Smiles	CC2(C)SC(C3=CC=CC=C3)(CCCNC)C1=CC=CC=C12.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for Talsupram hydrochloride

References are publications that support the biological activity of the product.

Schou Synthesis and positron emission tomography evaluation of three NE transporter radioligands: [C-11]desipramine, [C-11]talopram and [C-11]talsupram. Mol.Imaging Biol.
Rowlett Cocaine-like discriminative stimulus effects of heroin: modulation by selective monoamine transport inhibitors. J.Pharmacol.Exp.Ther. 2004 PMID: 14985417
McConathy Synthesis and biological evaluation of [¹¹C]talopram and [¹¹C]talsupram: candidate PET ligands for the NE transporter. Nucl.Med.Biol. 2004 PMID: 15246361

Talsupram hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 4352

Key Product Details

Biological Activity for Talsupram hydrochloride

Technical Data for Talsupram hydrochloride

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for Talsupram hydrochloride

Product Documents for Talsupram hydrochloride

COA

Certificate of Analysis

SDS

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