SHIP 2a
Tocris Bioscience, part of Bio-Techne | Catalog # 6101
Cystathione γ lyase (CSE) inhibitor
Discontinued Product
6101 has been discontinued.
View all Deaminase Inhibitors products.
Product Description
SHIP 2a is a cystathione γ lyase (CSE) inhibitor (IC50 = 6.3 μM). Inhibits H2S production in mouse aorta homogenates and L-cysteine-induced relaxation of rat aortic rings ex vivo.Product Specifications
Molecular Weight
184.22
Formula
C7H8N2O2S
Storage
Store at +4°C
Purity
≥98% (HPLC)
Chemical Name
(R)-2-Oxo-N-2-propyn-1-yl-4-thiazolidinecarboxamide
CAS Number
2165706-30-7
PubChem ID
124221753
InChI Key
MWEQVHWJNCRXGP-YFKPBYRVSA-N
SMILES
O=C([C@@H]1CSC(N1)=O)NCC#C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 18.42 | 100 | |
| Ethanol | 9.21 | 50 |
Preparing Stock Solutions
for SHIP 2a
The following data is based on the product molecular weight 184.22
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 5.43 mL | 27.14 mL | 54.28 mL |
| 5 mM | 1.09 mL | 5.43 mL | 10.86 mL |
| 10 mM | 0.54 mL | 2.71 mL | 5.43 mL |
| 50 mM | 0.11 mL | 0.54 mL | 1.09 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Corvino Fragment-based de novo design of a cystathionine γ-lyase selective inhibitor blocking hydrogen sulfide production. Sci.Rep. 2016 PMID: 27708394
Product Specific Notices for SHIP 2a
For research use only
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