SDZ 220-581

Tocris Bioscience, part of Bio-Techne | Catalog # 1250

Competitive NMDA antagonist
Discontinued Product
1250 has been discontinued. View all NMDA Receptor Antagonists products.

Key Product Details

Description

Competitive NMDA antagonist

View all NMDA Receptor Antagonists »

Product Description

SDZ 220-581 is a competitive NMDA receptor antagonist (pKi = 7.7). Centrally active following oral administration (ED50 < 3.2 mg/kg for protection against MES-induced seizures).

Licensing Information

Sold with the permission of Novartis Pharma AG

Product Specifications

Molecular Weight

369.74

Formula

C16H17ClNO5P

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

(S)-α-Amino-2'-chloro-5-(phosphonomethyl)[1,1'-biphenyl]-3-propanoic acid

CAS Number

174575-17-8

PubChem ID

128019

InChI Key

VBRJFXSFCYEZMQ-HNNXBMFYSA-N

SMILES

OC([C@@H](N)CC1=CC(C2=CC=CC=C2Cl)=CC(CP(O)(O)=O)=C1)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
1.1eq. NaOH 36.97 100
DMSO 9.24 25 with gentle warming

Preparing Stock Solutions for SDZ 220-581

The following data is based on the product molecular weight 369.74

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.70 mL 13.52 mL 27.05 mL
5 mM 0.54 mL 2.70 mL 5.41 mL
10 mM 0.27 mL 1.35 mL 2.70 mL
50 mM 0.05 mL 0.27 mL 0.54 mL

Calculators

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Product Documents for SDZ 220-581

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for SDZ 220-581

For research use only

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