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(S)-(-)-Sulpiride

Non-selective Dopamine Receptor Antagonists Small Molecule
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0895/100

Key Product Details

Description: Standard selective D2-like antagonist
Chemical Name: (S)-(-)-5-Aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide
Purity: ≥99% (HPLC)
Molecular Weight: 341.42

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  • Selective block of dopamine receptors
    Name: Sergiy Sylantyev
    Species: Human
    Cell Line/Tissue: Stem cell - derived neurons
    (S)‐sulpiride (Sul) was in use to block D2 dopamine receptors and thus prevent D2-mediated suppression of NMDA receptors response. The compound worked as expected, generating a discernible increase of amplitudes of NMDA-receptor – mediated evoked post-synaptic potentials in cultured dopamine neurons when applied with SCH‐23390 (see illustration). No problem with dissolution in DMSO for 10 mM stock.
    (S)-(-)-Sulpiride Serum 0895

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