S-Isopropylisothiourea hydrobromide

Name: S -Isopropylisothiourea hydrobromide
Brand: tocris
SKU: 0897

Catalog # 0897

Datasheet / COA / SDS

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$35 to United States

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Key Product Details

Description:	iNOS inhibitor, acts at arginine binding site
Molecular Weight:	199.11

View Full Technical Details for S-Isopropylisothiourea hydrobromide

Technical Data
Citations / Reviews

Biological Activity

Potent inhibitor of NO synthase, with selectivity for the inducible form.

Technical Data

M. Wt	199.11
Formula	C₄H₁₀N₂S.HBr
Storage	Store at RT
CAS Number	4269-97-0
PubChem ID	9813062
InChi Key	SLGVZEOMLCTKRK-UHFFFAOYSA-N
Smiles	Br.CC(C)SC(=N)N

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	19.91	100

Preparing Stock Solutions

The following data is based on the product molecular weight 199.11.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	5.02 mL	25.11 mL	50.22 mL
5 mM	1.00 mL	5.02 mL	10.04 mL
10 mM	0.50 mL	2.51 mL	5.02 mL
50 mM	0.10 mL	0.50 mL	1.00 mL

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Reconstitution Calculator

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References

References are publications that support the biological activity of the product.

Garvey Potent and selective inhibition of human nitric oxide synthases. J.Biol.Chem. 1994 PMID: 7523409
Moore and Handy Selective inhibitors of neuronal nitric oxide synthase - is no NOS really good NOS for the nervous system? TiPS 1997 PMID: 9226999
Handy Effect of S-methylisothiourea on neuronal nitric oxide synthase, nociception and blood pressure in the mouse. Br.J.Pharmacol.