(RS)-(Tetrazol-5-yl)glycine

Name: ( RS )-(Tetrazol-5-yl)glycine
Brand: tocris
SKU: 0312

Catalog # 0312

Datasheet / COA / SDS

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Key Product Details

Description:	Highly potent NMDA agonist
Purity:	≥98% (HPLC)
Molecular Weight:	143.1

View Full Technical Details for (RS)-(Tetrazol-5-yl)glycine

Biological Activity

Potent NMDA receptor agonist, approximately 20 times more active than NMDA.

Technical Data

M. Wt	143.1
Formula	C₃H₅N₅O₂
Storage	Store at RT
Purity	≥98% (HPLC)
CAS Number	138199-51-6
PubChem ID	126383
InChi Key	UKBRUIZWQZHXFL-UHFFFAOYSA-N
Smiles	NC(C(O)=O)C1=NN=NN1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water		50

Preparing Stock Solutions

The following data is based on the product molecular weight 143.1.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.5 mM	13.98 mL	69.88 mL	139.76 mL
2.5 mM	2.80 mL	13.98 mL	27.95 mL
5 mM	1.40 mL	6.99 mL	13.98 mL
25 mM	0.28 mL	1.40 mL	2.80 mL

Molarity Calculator

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Reconstitution Calculator

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References

References are publications that support the biological activity of the product.

Arnt Diffentiation of in vivo effects of AMPA and NMDA receptor ligands using drug discrimination methods and convulsant/anticonvulsant activity. Eur.J.Pharmacol. 1995 PMID: 8575516
Moroni NMDA receptor heterogeneity in mammalian tissues: focus on two agonists, (2S,3R,4S)cyclopropylglutamate and the sulfate ester of 4-hydroxy-(S)-pipecolic acid. Naunyn Schmiedebergs Arch.Pharmacol. 1995 PMID: 7543185
Schoepp D,L-(Tetrazol-5-yl)glycine a novel and highly potent NMDA receptor agonist. Eur.J.Pharmacol. 1991 PMID: 1686860