(RS)-3,4-DCPG
Tocris Bioscience, part of Bio-Techne | Catalog # 1394
Potent systemically active anticonvulsant. Racemate of (R)-3,4,-DCPG (Cat. No. 1395)
Discontinued Product
1394 has been discontinued.
View all iGluR Antagonists products.
Key Product Details
Description
Potent systemically active anticonvulsant. Racemate of (R)-3,4,-DCPG (Cat. No. 1395)
Product Description
(RS)-3,4-DCPG is a systemically active anticonvulsant that is 30-100-fold more potent in vivo than the separate enantiomers (S)-3,4-DCPG or (R)-3,4,-DCPG.S-enantiomer and R-enantiomer also available.
Product Specifications
Molecular Weight
239.18
Formula
C10H9NO6
Storage
Desiccate at RT
Purity
≥99% (HPLC)
Chemical Name
(RS)-3,4-Dicarboxyphenylglycine
CAS Number
176796-64-8
PubChem ID
3313698
InChI Key
IJVMOGKBEVRBPP-UHFFFAOYSA-N
SMILES
NC(C(O)=O)C1=CC=C(C(O)=O)C(=C1)C(O)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 50 |
Preparing Stock Solutions
for (RS)-3,4-DCPG
The following data is based on the product molecular weight 239.18
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.5 mM | 8.36 mL | 41.81 mL | 83.62 mL |
| 2.5 mM | 1.67 mL | 8.36 mL | 16.72 mL |
| 5 mM | 0.84 mL | 4.18 mL | 8.36 mL |
| 25 mM | 0.17 mL | 0.84 mL | 1.67 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Thomas Dicarboxyphenylglycines antagonize AMPA- but not kainate-induced depolarizations in neonatal rat motoneurones. Eur.J.Pharmacol. 1997 PMID: 9455991
- Thomas Pharmacological differentiation of kainate receptors on neonatal rat spinal motoneurones and dorsal roots. Neuropharmacology 1998 PMID: 9849660
- Moldrich Anticonvulsant activity of 3,4-dicarboxyphenylglycines in DBA/2 mice. Neuropharmacology 2001 PMID: 11311902
Product Specific Notices for (RS)-3,4-DCPG
For research use only
Loading...
Loading...