Rac1 Inhibitor W56
Tocris Bioscience, part of Bio-Techne | Catalog # 2221
Selective inhibitor of Rac1-GEF interaction
Discontinued Product
2221 has been discontinued.
View all Rho GTPase Inhibitors products.
Key Product Details
Description
Selective inhibitor of Rac1-GEF interaction
Product Description
Rac1 Inhibitor W56 is a peptide comprising residues 45-60 of the guanine nucleotide exchange factor (GEF) recognition/activation site of Rac1; selectively inhibits Rac1 interaction with Rac1-specific GEFs TrioN, GEF-H1 and Tiam1.Control Peptide also available.
Product Specifications
Molecular Weight
1671.93
Formula
C74H117N19O23S
Storage
Desiccate at -20°C
CAS Number
1095179-01-3
PubChem ID
90488750
InChI Key
IRORVMNZPUKWEX-YRMQSWGASA-N
SMILES
[H]N[C@@H](CCSC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)NCC(O)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 2mg/ml in PBS (pH 7.4) |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Gao Trp56 of Rac1 specifies interaction with a subset of guanine nucleotide exchange factors. J.Biol.Chem. 2001 PMID: 11595749
Product Specific Notices for Rac1 Inhibitor W56
For research use only
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