Quinelorane hydrochloride
Tocris Bioscience, part of Bio-Techne | Catalog # 1519
D2 and D3 agonist
Discontinued Product
1519 has been discontinued.
View all Non-selective Dopamine Receptor Agonists products.
Key Product Details
Description
D2 and D3 agonist
Alternative Names
LY 163502
Product Description
Quinelorane hydrochloride is a dopamine D2 and D3 receptor agonist; Ki values are 5.7 and 3.4 nM respectively.Licensing Information
Sold with the permission of Eli Lilly and CompanyProduct Specifications
Molecular Weight
319.27
Formula
C14H22N4.2HCl
Storage
Desiccate at RT
Purity
≥99% (HPLC)
Chemical Name
(5aR,9aR)-5,5a,6,7,8,9,9a,10-Octahydro-6-propylpyrido[2,3-g]quinazolin-2-amine dihydrochloride
CAS Number
97548-97-5
PubChem ID
68728
InChI Key
WDEMLQIGYYLRRX-OWVUFADGSA-N
SMILES
[H][C@]23[C@@](CCCN3CCC)([H])CC1=NC(N)=NC=C1C2.Cl.Cl
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 7.98 | 25 |
Preparing Stock Solutions
for Quinelorane hydrochloride
The following data is based on the product molecular weight 319.27
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.25 mM | 12.53 mL | 62.64 mL | 125.29 mL |
| 1.25 mM | 2.51 mL | 12.53 mL | 25.06 mL |
| 2.5 mM | 1.25 mL | 6.26 mL | 12.53 mL |
| 12.5 mM | 0.25 mL | 1.25 mL | 2.51 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Eaton Effects of the selective DArgic D2 agonist quinelorane on the activity of DArgic and noradrenergic neurons projecting to the diencephalon of the rat. J.Pharmacol.Exp.Ther. 1994 PMID: 7906734
- Flietstra and Levant Comparison of D2 and D3 DA receptor affinity of DArgic compounds in the rat brain. Life Sci. 1998 PMID: 9600324
- Foreman Preclinical studies on quinelorane, a potent and highly selective D2-DArgic agonist. J.Pharmacol.Exp.Ther. 1989 PMID: 2526214
Product Specific Notices for Quinelorane hydrochloride
For research use only
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