PNU 177864 hydrochloride

Name: PNU 177864 hydrochloride
Brand: Tocris Bioscience
SKU: 3355

Tocris Bioscience, part of Bio-Techne | Catalog # 3355

COA / SDS

Highly selective D3 antagonist

Discontinued Product

3355 has been discontinued. View all Dopamine D3 Receptor Antagonists products.

Key Product Details

Description:	Highly selective D₃ antagonist
Chemical Name:	N-[4-[2-(Propylamino)ethyl)phenyl]-4-(trifluoromethoxy)-benzenesulfonamide hydrochloride
Purity:	≥99% (HPLC)
Molecular Weight:	438.89

View Full Technical Details for PNU 177864 hydrochloride

Technical Data
Citations

Biological Activity for PNU 177864 hydrochloride

PNU 177864 hydrochloride is a highly selective dopamine D₃ receptor antagonist. Induces phospholipidosis and exhibits antischizophrenic activity in vivo.

Technical Data for PNU 177864 hydrochloride

M. Wt	438.89
Formula	C₁₈H₂₁F₃N₂O₃S.HCl
Storage	Desiccate at RT
Purity	≥99% (HPLC)
CAS Number	1783978-03-9
PubChem ID	56972219
InChi Key	UOMDLHQTLPWCCE-UHFFFAOYSA-N
Smiles	O=S(C1=CC=C(OC(F)(F)F)C=C1)(NC2=CC=C(CCNCCC)C=C2)=O.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for PNU 177864 hydrochloride

References are publications that support the biological activity of the product.

Rudmann Epididymal and systemic phospholipidosis in rats and dogs treated with DA D3 selective antagonist PNU-177864. Toxicol.Pathol. 2004 PMID: 15204974
Vonderfecht Myopathy related to administration of a cationic amphiphilic drug and the use of multidose drug distribution analysis to predict its occurrence. Toxicol.Pathol. 2004 PMID: 15204973

PNU 177864 hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 3355

Key Product Details

Biological Activity for PNU 177864 hydrochloride

Technical Data for PNU 177864 hydrochloride

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for PNU 177864 hydrochloride

Product Documents for PNU 177864 hydrochloride

COA

Certificate of Analysis

SDS

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