(+)-Abscisic Acid
Tocris Bioscience, part of Bio-Techne | Catalog # 6554
Endogenous LANCL2 agonist
Discontinued Product
6554 has been discontinued.
View all Other Synthase/Synthetase Compounds products.
Key Product Details
Description
Endogenous LANCL2 agonist
Product Description
(+)-Abscisic Acid is an endogenous lanthionine synthetase C-like 2 (LANCL2) ligand. Stimulates glucose uptake by myocytes and pre-adipocytes in vitro, and by brown adipose tissue in vivo. Acts as a pro-inflammatory modulator of innate immune system cells. Stimulates proliferation of human mesenchymal and hematopoietic stem cells. Also used to control Cas9 via a RNA polymerase-based biosensor.Product Specifications
Molecular Weight
264.32
Formula
C15H20O4
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
(2Z,4E)-5-[(1S)-1-Hydroxy-2,6,6-trimethyl-4-oxo-2-cyclohexen-1-yl]-3-methyl-2,4-pentadienoic acid
CAS Number
21293-29-8
PubChem ID
5280896
InChI Key
JLIDBLDQVAYHNE-YKALOCIXSA-N
SMILES
CC(/C=C/[C@]1(C(C)=CC(CC1(C)C)=O)O)=C/C(O)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 26.43 | 100 | |
| Ethanol | 26.43 | 100 |
Preparing Stock Solutions
for (+)-Abscisic Acid
The following data is based on the product molecular weight 264.32
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.78 mL | 18.92 mL | 37.83 mL |
| 5 mM | 0.76 mL | 3.78 mL | 7.57 mL |
| 10 mM | 0.38 mL | 1.89 mL | 3.78 mL |
| 50 mM | 0.08 mL | 0.38 mL | 0.76 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Pu Multidimensional control of Cas9 by evolved RNA polymerase-based biosensors. ACS Chem.Biol. 2018 PMID: 28809467
- Fresia G-protein coupling and nuclear translocation of the human abscisic acid receptor LANCL2. Sci.Rep. 2016 PMID: 27222287
- Sturla Abscisic acid enhances glucose disposal and induces brown fat activity in adipocytes in vitro and in vivo. Biochim.Biophys.Acta. 2017 PMID: 27871880
- Carbo An N,N-Bis(benzimidazolylpicolinoyl)piperazine (BT-11): A novel lanthionine synthetase C-Like 2-based therapeutic for inflammatory bowel disease. J.Med.Chem. 2016 PMID: 27933891
Product Specific Notices for (+)-Abscisic Acid
For research use only
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