Phenserine

Tocris Bioscience, part of Bio-Techne | Catalog # 2967

Cholinesterase inhibitor
Discontinued Product
2967 has been discontinued. View all Cholinesterase Inhibitors products.

Key Product Details

Description

Cholinesterase inhibitor

View all Cholinesterase Inhibitors »

Product Description

Physostigmine analog that inhibits acetylcholinesterase. Inhibits production of amyloid precursor protein (APP) and Aβ. Improves morris water maze performance of scopolamine-treated rats.

Product Specifications

Molecular Weight

337.42

Formula

C20H23N3O2

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

(3aS,8aR)-1,2,3,3a,8,8a-Hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indol-5-ol 5-(N-phenylcarbamate)

CAS Number

101246-66-6

PubChem ID

192706

InChI Key

PBHFNBQPZCRWQP-QUCCMNQESA-N

SMILES

O=C(OC2=CC=C(N(C)[C@]4([H])[C@](C)3CCN4C)C3=C2)NC1=CC=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 3.37 10
Ethanol 8.44 25

Preparing Stock Solutions for Phenserine

The following data is based on the product molecular weight 337.42

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.25 mM 11.85 mL 59.27 mL 118.55 mL
1.25 mM 2.37 mL 11.85 mL 23.71 mL
2.5 mM 1.19 mL 5.93 mL 11.85 mL
12.5 mM 0.24 mL 1.19 mL 2.37 mL

Calculators

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for Phenserine

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Phenserine

For research use only

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