PETCM

Name: PETCM
Brand: Tocris Bioscience
SKU: 1758

Tocris Bioscience, part of Bio-Techne | Catalog # 1758

COA / SDS

Activator of caspase-3

Discontinued Product

1758 has been discontinued. View all Caspase Activators products.

Key Product Details

Description:	Activator of caspase-3
Chemical Name:	α-(Trichloromethyl)-4-pyridineethanol
Purity:	≥99% (HPLC)
Molecular Weight:	240.52

View Full Technical Details for PETCM

Technical Data
Citations

Biological Activity for PETCM

PETCM is a caspase-3 activator. Acts via inhibition of the oncoprotein ProT, therefore stimulates apoptosome formation and subsequent caspase-3 activation in a cytochrome c-dependent manner.

Technical Data for PETCM

M. Wt	240.52
Formula	C₈H₈Cl₃NO
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	10129-56-3
PubChem ID	224859
InChi Key	NGTDJJKTGRNNAU-UHFFFAOYSA-N
Smiles	OC(CC1=CC=NC=C1)C(Cl)(Cl)Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for PETCM

References are publications that support the biological activity of the product.

Nguyen and Wells Direct activation of the apoptosis machinery as a mechanism to target cancer cells. Proc.Natl.Acad.Sci.U.S.A. 2003 PMID: 12808146
Jiang Distinctive roles of PHAP proteins and prothymosin-α in a death regulatory pathway. Science 2003 PMID: 12522243

PETCM

Tocris Bioscience, part of Bio-Techne | Catalog # 1758

Key Product Details

Biological Activity for PETCM

Technical Data for PETCM

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for PETCM

Product Documents for PETCM

COA

Certificate of Analysis

SDS

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