Pentobarbital sodium salt

Name: Pentobarbital sodium salt
Brand: Tocris Bioscience
SKU: 4579

Tocris Bioscience a Bio-Techne Brand

Catalog # 4579

Citations (1)

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Key Product Details

Description:	Enhances GABAergic activity
Chemical Name:	5-Ethyl-5-(1-methylbutyl)-2,4,6(1H,3H,5H)-pyrimidinetrione sodium salt
Molecular Weight:	248.25

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Biological Activity for Pentobarbital sodium salt

Pentobarbital sodium salt enhances GABAergic activity. Pentobarbital is a short-acting barbiturate.

Technical Data for Pentobarbital sodium salt

M. Wt	248.25
Formula	C₁₁H₁₇N₂NaO₃
Storage	Store at RT
CAS Number	57-33-0
PubChem ID	14075609
InChi Key	QGMRQYFBGABWDR-UHFFFAOYSA-M
Smiles	[Na+].CCCC(C)C1(CC)C(=O)NC([O-])=NC1=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Pentobarbital sodium salt

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water	24.82	100

Preparing Stock Solutions for Pentobarbital sodium salt

The following data is based on the product molecular weight 248.25.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	4.03 mL	20.14 mL	40.28 mL
5 mM	0.81 mL	4.03 mL	8.06 mL
10 mM	0.40 mL	2.01 mL	4.03 mL
50 mM	0.08 mL	0.40 mL	0.81 mL

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References for Pentobarbital sodium salt

References are publications that support the biological activity of the product.

Steinbach and Akk Modulation of GABA_A receptor channel gating by pentobar. J.Physiol. 2001 PMID: 11744750

Citations for Pentobarbital sodium salt (1)

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Citations are publications that use Bio-Techne products. Selected citations for Pentobarbital sodium salt include:

Yan et al. (2016) MicroRNA-34a affects chondrocyte apoptosis and proliferation by targeting the SIRT1/p53 signaling pathway during the pathogenesis of osteoarthritis. Nat Commun. 38:201
PMID: 27247228

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