PD 150606

Tocris Bioscience, part of Bio-Techne | Catalog # 1269

Cell permeable calpain inhibitor
Discontinued Product
1269 has been discontinued. View all Calpain Inhibitors products.

Key Product Details

Description

Cell permeable calpain inhibitor

View all Calpain Inhibitors »

Product Description

PD 150606 is a selective, cell-permeable non-peptide calpain inhibitor (Ki values for ν and m-calpains are 0.21 and 0.37 μM respectively). Targets the calcium binding sites of calpain. Demonstrates high specificity for calpains relative to other proteases, and is a non-competitive inhibitor with respect to the substrate.

Product Specifications

Molecular Weight

306.12

Formula

C9H7IO2S

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

(Z)-3-(4-Iodophenyl)-2-mercapto-2-propenoic acid

CAS Number

179528-45-1

PubChem ID

9839500

InChI Key

DJCVSFWGKYHMKH-YVMONPNESA-N

SMILES

IC1=CC=C(/C=C(C(O)=O)\S)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 30.61 100
Ethanol 15.31 50

Preparing Stock Solutions for PD 150606

The following data is based on the product molecular weight 306.12

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.27 mL 16.33 mL 32.67 mL
5 mM 0.65 mL 3.27 mL 6.53 mL
10 mM 0.33 mL 1.63 mL 3.27 mL
50 mM 0.07 mL 0.33 mL 0.65 mL

Calculators

Molarity Calculator

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Dilution Calculator

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for PD 150606

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for PD 150606

For research use only

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