Pancuronium dibromide
Tocris Bioscience, part of Bio-Techne | Catalog # 0693
Neuromusclar nAChR antagonist
Discontinued Product
0693 has been discontinued.
View all Additional Nicotinic Receptor Antagonists products.
Key Product Details
Description
Neuromusclar nAChR antagonist
Product Description
Pancuronium dibromide is a nicotine (neuromuscular) antagonist. Skeletal muscle relaxant.Product Specifications
Molecular Weight
732.68
Formula
C35H60Br2N2O4
Storage
Desiccate at RT
Purity
≥99%
Chemical Name
1,1'-(3α,17β-Dihydroxy-2β,5α-androstan-2β,16β-ylene) bis[1-methylpiperidinium] diacetate dibromide
CAS Number
15500-66-0
PubChem ID
23581810
InChI Key
NPIJXCQZLFKBMV-TZJMVAHLSA-L
SMILES
[H][C@]34C2([H])CC[C@@]1([H])C[C@H](OC(C)=O)C([N+]6(C)CCCCC6)CC(C)1[C@]([H])2CCC(C)3C(OC(C)=O)C([N+]5(C)CCCCC5)C4.[Br-].[Br-]
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 73.27 | 100 |
Preparing Stock Solutions
for Pancuronium dibromide
The following data is based on the product molecular weight 732.68
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.36 mL | 6.82 mL | 13.65 mL |
| 5 mM | 0.27 mL | 1.36 mL | 2.73 mL |
| 10 mM | 0.14 mL | 0.68 mL | 1.36 mL |
| 50 mM | 0.03 mL | 0.14 mL | 0.27 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Lowenick Open channel and competitive block of nicotinic receptors by pancur. and atrac. Eur.J.Pharmacol. 2001 PMID: 11173060
- Maestrone Extracellular pancur. affects sodium current in chick embryo sensory neurones. Br.J.Pharmacol. 1994 PMID: 8012707
- Fryer and Maclagan Pancuronium and gallamine are antagonists for pre- and post-junctional muscarinic receptors in the guinea-pig lung. Naunyn Schmiedebergs Arch.Pharmacol. 1987 PMID: 3600815
Product Specific Notices for Pancuronium dibromide
For research use only
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