Olmesartan

Tocris Bioscience, part of Bio-Techne | Catalog # 4616

Potent AT1 antagonist
Discontinued Product
4616 has been discontinued. View all Angiotensin AT1 Receptor Antagonists products.

Key Product Details

Description

Potent AT1 antagonist

View all Angiotensin AT1 Receptor Antagonists »

Product Description

Olmesartan is a potent angiotensin II type I (AT1) receptor antagonist (IC50 = 6.7 nM at hAT1 receptors). Improves cognitive function in a mouse model of hypertension- and hyperlipidemia-associated cognitive decline; ameliorates arterial stiffness in a rat model of chronic renal failure.

Product Specifications

Molecular Weight

446.50

Formula

C24H26N6O3

Storage

Store at +4°C

Purity

≥99% (HPLC)

Chemical Name

4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic acid

CAS Number

144689-24-7

PubChem ID

158781

InChI Key

VTRAEEWXHOVJFV-UHFFFAOYSA-N

SMILES

CCCC1=NC(C(C)(C)O)=C(C(O)=O)N1CC2=CC=C(C3=CC=CC=C3C4=NN=NN4)C=C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 8.93 20

Preparing Stock Solutions for Olmesartan

The following data is based on the product molecular weight 446.50

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.2 mM 11.20 mL 55.99 mL 111.98 mL
1 mM 2.24 mL 11.20 mL 22.40 mL
2 mM 1.12 mL 5.60 mL 11.20 mL
10 mM 0.22 mL 1.12 mL 2.24 mL

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

x
=
x

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Background References

References are publications that support the biological activity of the product.

Product Documents for Olmesartan

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Olmesartan

For research use only

Privacy Policy
Cookie Policy
Site Map
© Copyright 2026 Bio-Techne. All Rights Reserved. All trademarks and registered trademarks are the property of Bio-Techne and its brands unless otherwise specified.