O-1918

Name: O-1918
Brand: Tocris Bioscience
SKU: 2288

Tocris Bioscience, part of Bio-Techne | Catalog # 2288

Citations (26)

COA / SDS

Silent antagonist for putative abnormal-CBD (Cat. No. 1297) receptor

Discontinued Product

2288 has been discontinued. View all Additional Cannabinoid-related Compounds products.

Key Product Details

Description:	Silent antagonist for putative abnormal-CBD (Cat. No. 1297) receptor
Chemical Name:	1,3-Dimethoxy-5-methyl-2-[(1R,6R)-3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]benzene
Purity:	≥97% (HPLC)
Molecular Weight:	286.41

View Full Technical Details for O-1918

Technical Data
Citations

Biological Activity for O-1918

O-1918 is a selective, silent antagonist of a putative endothelial anandamide receptor distinct from CB₁ or CB₂ receptors. Inhibits vasodilation and cell migration induced by abnormal-cannabidiol (abn-CBD; Cat. No. 1297).

Licensing Information

Sold under license from the NIH, US patent 60/312,674

Technical Data for O-1918

M. Wt	286.41
Formula	C₁₉H₂₆O₂
Storage	Store at -20°C
Purity	≥97% (HPLC)
CAS Number	536697-79-7
PubChem ID	40469923
InChi Key	ICHJMVMWPKLUKT-JKSUJKDBSA-N
Smiles	COC1=CC(C)=CC(OC)=C1[C@@H]1C=C(C)CC[C@H]1C(C)=C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for O-1918

References are publications that support the biological activity of the product.

Mo Atypical cannabinoid stimulates endothelial cell migration via a G_i/G_o coupled receptor distinct from CB₁, CB₂ or EDG-1. Eur.J.Pharmacol. 2004 PMID: 15063151
Hoi and Hiley Vasorelaxant effects of oleamide in rat small mesenteric artery indicate action at a novel cannabinoid receptor. Br.J.Pharmacol. 2006 PMID: 16415907
Offertáler Selective ligands and cellular effectors of a G protein-coupled endothelial cannabinoid receptor. Mol.Pharmacol. 2003 PMID: 12606780