Selective DNA-PK inhibitor
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Key Product Details
Description: | Selective DNA-PK inhibitor |
Chemical Name: | 2-(4-Morpholinyl)-4H-naphthol[1,2-b]pyran-4-one |
Purity: | ≥98% (HPLC) |
Molecular Weight: | 281.31 |
Citations for NU 7026 (14)
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Citations are publications that use Bio-Techne products. Selected citations for NU 7026 include:
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Jaiswal et al.
(2017)
ATM/Wip1 activities at chromatin control Plk1 re-activation to determine G2 checkpoint duration.
EMBO J.
36:2161
PMID: 28607002 -
You et al.
(2015)
Nanoparticulate carbon black in cigarette smoke induces DNA cleavage and Th17-mediated emphysema.
Elife.
4
PMID: 26437452 -
Dolman et al.
(2015)
DNA-Dependent Protein Kinase As Molecular Target for Radiosensitization of Neuroblastoma Cells.
PLoS One.
10:e0145744
PMID: 26716839 -
Nakahara et al.
(2015)
Activation of NF-κB by human papillomavirus 16 E1 limits E1-dependent viral replication through degradation of E1.
Chembiochem.
89:5040
PMID: 25717108 -
Rodgers et al.
(2015)
Spatio-temporal regulation of RAG2 following genotoxic stress.
DNA Repair (Amst).
27:19
PMID: 25625798 -
Allen et al.
(2015)
DNA Damage Response Proteins and Oxygen Modulate Prostaglandin E2 Growth Factor Release in Response to Low and High LET Ionizing Radiation.
Front Oncol.
5:260
PMID: 26697402 -
Yousefzadeh et al.
(2014)
Mechanism of suppression of chromosomal instability by DNA polymerase POLQ.
PLoS Genet.
10:e1004654
PMID: 25275444 -
Fard et al.
(2013)
The heterogenic final cell cycle of chicken retinal Lim1 horizontal cells is not regulated by the DNA damage response pathway.
Cell Cycle.
13:408
PMID: 24247150 -
Sultana et al.
(2013)
Targeting XRCC1 deficiency in breast cancer for personalized therapy.
Cancer Res.
73:1621
PMID: 23253910 -
Petruccelli et al.
(2013)
Expression of leukemia-associated fusion proteins increases sensitivity to histone deacetylase inhibitor-induced DNA damage and apoptosis.
Mol Cancer Ther.
12:1591
PMID: 23536727 -
Tang et al.
(2012)
Detection of early Abl kinase activation after ionizing radiation by using a peptide biosensor.
J Neurosci.
13:665
PMID: 22334513 -
Kanai et al.
(2012)
Oncolytic virus-mediated manipulation of DNA damage responses: synergy with chemotherapy in killing glioblastoma stem cells.
J Natl Cancer Inst.
104:42
PMID: 22173583 -
Ando et al.
(2012)
PIDD death-domain phosphorylation by ATM controls prodeath versus prosurvival PIDDosome signaling.
Mol Cell.
47:681
PMID: 22854598 -
Bohgaki et al.
(2011)
Genomic instability, defective spermatogenesis, immunodeficiency, and cancer in a mouse model of the RIDDLE syndrome.
PLoS Genet.
7:e1001381
PMID: 21552324
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Customer Reviews for NU 7026 (1)
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Species: HumanAssay Type: In VitroCell Line/Tissue: U2OSI used the DNA-PK inhibitor (NU7026) to treat human osteosarcoma cells (U2OS) and assessed if the inhibition worked by blotting for pDNA-PKcs (S2056). The inhibitor works extremely well!
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