NPEC-caged-(S)-AMPA

Name: NPEC-caged-( S )-AMPA
Brand: Tocris Bioscience
SKU: 3840

Catalog # 3840 | Tocris Bioscience a Bio-Techne Brand

COA / SDS

Caged (S)-AMPA

Discontinued Product

3840 has been discontinued. View all AMPA Receptor Agonists products.

Key Product Details

Description:	Caged (S)-AMPA
Chemical Name:	(N)-1-(2-Nitrophenyl)ethylcarboxy-(S)-α-1-(2-nitrophenyl)ethylcarboxyamino-3-hydroxy-5-methyl-4-isoxazolepropionic acid
Purity:	≥98% (HPLC)
Molecular Weight:	379.32

View Full Technical Details for NPEC-caged-(S)-AMPA

Technical Data
Citations / Reviews

Biological Activity for NPEC-caged-(S)-AMPA

NPEC-caged-(S)-AMPA is a 1-(2-nitrophenyl)ethyl caged version of (S)-AMPA (Cat. No. 0254), agonist at the AMPA receptor. Extinction coefficient (ε₃₄₇) = 660 M^-1cm^-1, quantum yield (φ) = 0.64. Suitable for near-UV uncaging. No inhibition of GABA-A receptors at concentrations used experimentally.

Technical Data for NPEC-caged-(S)-AMPA

M. Wt	379.32
Formula	C₁₆H₁₇N₃O₈
Storage	Store at -20°C
Purity	≥98% (HPLC)
CAS Number	1257323-84-4
PubChem ID	90488885
InChi Key	LGVJRWDYNJZRRP-MYIOLCAUSA-N
Smiles	[H][C@@](NC(OC(C)C2=CC=CC=C2[N+]([O-])=O)=O)(C(O)=O)CC1=C(C)ON=C1O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for NPEC-caged-(S)-AMPA

References are publications that support the biological activity of the product.

Palma-Cerda New caged neurotransmitter analogs selective for glutamate receptor sub-types based on methoxynitroindoline and nitrophenylethoxycarbonyl caging groups. Neuropharmacology. 2012 PMID: 22609535

Citations for NPEC-caged-(S)-AMPA

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