NPEC-caged-(S)-AMPA
Tocris Bioscience, part of Bio-Techne | Catalog # 3840
Caged (S)-AMPA
Discontinued Product
3840 has been discontinued.
View all AMPA Receptor Agonists products.
Product Description
NPEC-caged-(S)-AMPA is a 1-(2-nitrophenyl)ethyl caged version of (S)-AMPA (Cat. No. 0254), agonist at the AMPA receptor. Extinction coefficient (ε347) = 660 M-1cm-1, quantum yield (φ) = 0.64. Suitable for near-UV uncaging. No inhibition of GABA-A receptors at concentrations used experimentally.Product Specifications
Molecular Weight
379.32
Formula
C16H17N3O8
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
(N)-1-(2-Nitrophenyl)ethylcarboxy-(S)-α-1-(2-nitrophenyl)ethylcarboxyamino-3-hydroxy-5-methyl-4-isoxazolepropionic acid
CAS Number
1257323-84-4
PubChem ID
90488885
InChI Key
LGVJRWDYNJZRRP-MYIOLCAUSA-N
SMILES
[H][C@@](NC(OC(C)C2=CC=CC=C2[N+]([O-])=O)=O)(C(O)=O)CC1=C(C)ON=C1O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 1.9 | 5 with gentle warming | |
| DMSO | 37.93 | 100 |
Preparing Stock Solutions
for NPEC-caged-(S)-AMPA
The following data is based on the product molecular weight 379.32
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.64 mL | 13.18 mL | 26.36 mL |
| 5 mM | 0.53 mL | 2.64 mL | 5.27 mL |
| 10 mM | 0.26 mL | 1.32 mL | 2.64 mL |
| 50 mM | 0.05 mL | 0.26 mL | 0.53 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Palma-Cerda New caged neurotransmitter analogs selective for glutamate receptor sub-types based on methoxynitroindoline and nitrophenylethoxycarbonyl caging groups. Neuropharmacology. 2012 PMID: 22609535
Product Specific Notices for NPEC-caged-(S)-AMPA
For research use only
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