Nitrocaramiphen hydrochloride

Name: Nitrocaramiphen hydrochloride
Brand: Tocris Bioscience
SKU: 0469

Tocris Bioscience a Bio-Techne Brand

Catalog # 0469

COA / SDS

Discontinued Product

0469 has been discontinued. View all mAChR M1 Antagonists products.

Key Product Details

Description:	Muscarinic antagonist, M₁ > M₂
Chemical Name:	2-Diethylaminoethyl 1-(4-nitrophenyl)cyclopentanecarboxylate hydrochloride
Purity:	≥98% (HPLC)
Molecular Weight:	370.88

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Biological Activity for Nitrocaramiphen hydrochloride

Nitrocaramiphen hydrochloride is a muscarinic antagonist with 71-fold selectivity for M₁ over M₂.

Technical Data for Nitrocaramiphen hydrochloride

M. Wt	370.88
Formula	C₁₈H₂₆N₂O₄.HCl
Storage	Store at RT
Purity	≥98% (HPLC)
CAS Number	98636-73-8
PubChem ID	25102587
InChi Key	XWQWACGTGFICFO-UHFFFAOYSA-N
Smiles	O=C(OCCN(CC)CC)C2(CCCC2)C1=CC=C([N+]([O-])=O)C=C1.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Nitrocaramiphen hydrochloride

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water		10

Preparing Stock Solutions for Nitrocaramiphen hydrochloride

The following data is based on the product molecular weight 370.88.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.96 mL	134.81 mL	269.63 mL
0.5 mM	5.39 mL	26.96 mL	53.93 mL
1 mM	2.70 mL	13.48 mL	26.96 mL
5 mM	0.54 mL	2.70 mL	5.39 mL

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Reconstitution Calculator

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References for Nitrocaramiphen hydrochloride

References are publications that support the biological activity of the product.

Hudkins Caramiphen, iodocaramiphen and nitrocaramiphen are potent, competitive, muscarine M₁ receptor selective agents. Eur.J.Pharmacol. 1993 PMID: 8449241
Hudkins Muscarinic receptor binding. Profile of para-sustituted caramiphen analogues. J.Med.Chem 1991 PMID: 1920350

Citations for Nitrocaramiphen hydrochloride

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Product Documents for Nitrocaramiphen hydrochloride

COA

Certificate of Analysis is currently unavailable on-line. Please contact Customer Service.