Niflumic acid

Name: Niflumic acid
Brand: Tocris Bioscience
SKU: 4112
Rating: 5 (1 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 4112

(1)

Citations (3)

COA / SDS

Cyclooxygenase-2 (COX-2) inhibitor; GPR35 agonist

Discontinued Product

4112 has been discontinued. View all Cyclooxygenase Inhibitors products.

Key Product Details

Description:	Cyclooxygenase-2 (COX-2) inhibitor; GPR35 agonist
Chemical Name:	2-[3-(Trifluoromethyl)anilino]nicotinic acid
Molecular Weight:	282.22

View Full Technical Details for Niflumic acid

Technical Data
Citations / Reviews (1)

Biological Activity for Niflumic acid

Niflumic acid is a nonsteroidal anti-inflammatory drug (NSAID); selectively inhibits COX-2. Also activates human TRPA1 inducibly expressed in HEK293 cells; displays agonist activity at GPR35.

Technical Data for Niflumic acid

M. Wt	282.22
Formula	C₁₃H₉F₃N₂O₂
Storage	Store at RT
CAS Number	4394-00-7
PubChem ID	4488
InChi Key	JZFPYUNJRRFVQU-UHFFFAOYSA-N
Smiles	O=C(C1=CC=CN=C1NC2=CC=CC(C(F)(F)F)=C2)O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

References for Niflumic acid

References are publications that support the biological activity of the product.

Deng Multiple tyrosine metabolites are GPR35 agonists. Sci.Rep. 2012 PMID: 22523636
Famaey In vitro and in vivo pharmacological evidence of selective cyclooxygenase-2 inhibition by nimesulide: an overview. Inflamm.Res. 1997 PMID: 9427063
Hu Activation of TRPA1 channels by fenamate nonsteroidal anti-inflammatory drugs. Pflugers Arch. 2010 PMID: 19888597
Ottolia and Toro Potentiation of large conductance KCa channels by niflumic, flufenamic and mefenamic acids. Biophys.J. 1994 PMID: 7535111

Niflumic acid

Tocris Bioscience, part of Bio-Techne | Catalog # 4112

Key Product Details

Biological Activity for Niflumic acid

Technical Data for Niflumic acid

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for Niflumic acid

Product Documents for Niflumic acid

COA

Certificate of Analysis

SDS

CONTACT INFORMATION

Stay Connected