Naltriben mesylate

Name: Naltriben mesylate
Brand: tocris
SKU: 0892

Catalog # 0892

Citations (1)

Datasheet / COA / SDS

Order Information

Bio-Techne Corporation

tel: (612) 379-2956

tel: (800) 343-7475 (free phone)

customercare.na@bio-techne.com

Shipping Information

$35 to United States

Products in stock will be shipped in 1-3 business days unless specified.

View Distributors

Key Product Details

Description:	Standard δ₂ selective antagonist
Chemical Name:	17-(Cyclopropylmethyl)-6,7-didehydro-3,14β-dihydroxy-4,5α-epoxy-6,7-2',3'-benzo[b]furanomorphinan mesylate
Purity:	≥98% (HPLC)
Molecular Weight:	511.59

View Full Technical Details for Naltriben mesylate

Biological Activity

Selective and potent δ-opioid receptor antagonist (K_i values are 0.013, 19 and 152 nM for δ, μ and κ receptors respectively). Displays selectivity for the δ₂ subtype in vivo.

Licensing Information

Sold with the permission of the University of Minnesota

Technical Data

M. Wt	511.59
Formula	C₂₆H₂₅NO₄.CH₃SO₃H
Storage	Desiccate at RT
Purity	≥98% (HPLC)
CAS Number	122517-78-6
PubChem ID	45073482
InChi Key	XRRFZOCDAWPIBB-IDRHMUJXSA-N
Smiles	C[S](O)(=O)=O.[H][C@@]12OC3=C(O)C=CC4=C3[C@@]11CCN(CC3CC3)[C@]([H])(C4)[C@]1(O)CC1=C2OC2=C1C=CC=C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	25.58	50 with gentle warming

Preparing Stock Solutions

The following data is based on the product molecular weight 511.59.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.5 mM	3.91 mL	19.55 mL	39.09 mL
2.5 mM	0.78 mL	3.91 mL	7.82 mL
5 mM	0.39 mL	1.95 mL	3.91 mL
25 mM	0.08 mL	0.39 mL	0.78 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

References

References are publications that support the biological activity of the product.

Miyamoto Involvement of delta₂ opioid receptors in the development of mor. dependence in mice. J.Pharmacol.Exp.Ther. 1993 PMID: 8383738
Portoghese Role of spacer and address components in peptidomimetic δ opioid receptor antagonists related to naltrindole. J.Med.Chem. 1991 PMID: 1851846
Thorat and Hammond Modulation of nociception by microinjection of delta-1 and delta-2 opioid receptor ligands in the ventromedial medulla of the rat. J.Pharmacol.Exp.Ther. 1997 PMID: 9399992

Citations (1)

Showing 1 - 1 of 1 citation Showing All

Search Title:

Citations are publications that use Bio-Techne products. Selected citations for Naltriben mesylate include:

Gomes et al. (2000) Heterodimerization of μ and δ opioid receptors: A role in opiate synergy. Exp Neurobiol. 20:RC110
PMID: 11069979

There are no citations that match your criteria.

Showing 1 - 1 of 1 citation Showing All

Product Datasheets

COA

Certificate of Analysis

To download a Certificate of Analysis, please select a batch below.

SDS

Open modal

Naltriben mesylate

Order Information

Shipping Information

Key Product Details

Complete Your Research

Biological Activity

Licensing Information

Technical Data

Solubility

Preparing Stock Solutions

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References

Citations (1)

Product Datasheets

COA

Certificate of Analysis

SDS

Bio-Techne Brands

Stay Connected