Naltriben mesylate

Name: Naltriben mesylate
Brand: Tocris Bioscience
SKU: 0892

Tocris Bioscience, part of Bio-Techne | Catalog # 0892

Citations (4)

COA / SDS

Standard δ2 selective antagonist

Discontinued Product

0892 has been discontinued. View all delta Opioid Receptor Antagonists products.

Key Product Details

Description:	Standard δ₂ selective antagonist
Chemical Name:	17-(Cyclopropylmethyl)-6,7-didehydro-3,14β-dihydroxy-4,5α-epoxy-6,7-2',3'-benzo[b]furanomorphinan mesylate
Purity:	≥98% (HPLC)
Molecular Weight:	511.59

View Full Technical Details for Naltriben mesylate

Technical Data
Citations

Biological Activity for Naltriben mesylate

Naltriben mesylate is a selective and potent δ-opioid receptor antagonist (K_i values are 0.013, 19 and 152 nM for δ, μ and κ receptors respectively). Displays selectivity for the δ₂ subtype in vivo.

Licensing Information

Sold with the permission of the University of Minnesota

Technical Data for Naltriben mesylate

M. Wt	511.59
Formula	C₂₆H₂₅NO₄.CH₃SO₃H
Storage	Desiccate at RT
Purity	≥98% (HPLC)
CAS Number	122517-78-6
PubChem ID	45073482
InChi Key	XRRFZOCDAWPIBB-IDRHMUJXSA-N
Smiles	C[S](O)(=O)=O.[H][C@@]12OC3=C(O)C=CC4=C3[C@@]11CCN(CC3CC3)[C@]([H])(C4)[C@]1(O)CC1=C2OC2=C1C=CC=C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for Naltriben mesylate

References are publications that support the biological activity of the product.

Portoghese Role of spacer and address components in peptidomimetic δ opioid receptor antagonists related to naltrindole. J.Med.Chem. 1991 PMID: 1851846
Thorat and Hammond Modulation of nociception by microinjection of delta-1 and delta-2 opioid receptor ligands in the ventromedial medulla of the rat. J.Pharmacol.Exp.Ther. 1997 PMID: 9399992
Miyamoto Involvement of delta₂ opioid receptors in the development of mor. dependence in mice. J.Pharmacol.Exp.Ther. 1993 PMID: 8383738