N¹,N¹²-Diethylspermine tetrahydrochloride

Biological Activity

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

Preparing Stock Solutions

The following data is based on the product molecular weight 404.29.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

References

References are publications that support the biological activity of the product.

• Bergeron Synthesis and bioloigcal evaluation of aminopolyamines. J.Med.Chem. 2005 PMID: 15857111
• Vertino Selective cellular depletion of mitochondrial DNA by the polyamine analog N¹,N¹²-bis(ethyl)spermine and its relationship to polyamine structure and function. Mol.Pharmacol. 1991 PMID: 2017149
• Porter Combined regulation of arginine and S-adenosylmethionine decarboxylases by spermine and the spermine analogue N¹,N¹²-bis(ethyl)spermine. Biochem.J. 1990 PMID: 2344358
• Bergeron Synthetic polyamine analogues as antineoplastics. J.Med.Chem. 1988 PMID: 3373487