N-Acetyltryptamine

Name: N -Acetyltryptamine
Brand: Tocris Bioscience
SKU: 0357

Tocris Bioscience a Bio-Techne Brand

Catalog # 0357

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Key Product Details

Description:	Substrate for serotonin N-acetyl transferase
Purity:	≥99% (HPLC)
Molecular Weight:	202.26

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Biological Activity for N-Acetyltryptamine

N-Acetyltryptamine is a partial agonist for melatonin receptors in the retina. Also used for determination of serotonin N-acetyl transferase activity.

Compound Libraries for N-Acetyltryptamine

N-Acetyltryptamine is also offered as part of the Tocriscreen 2.0 Max. Find out more about compound libraries available from Tocris.

Technical Data for N-Acetyltryptamine

M. Wt	202.26
Formula	C₁₂H₁₄N₂O
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	1016-47-3
PubChem ID	70547
InChi Key	NVUGEQAEQJTCIX-UHFFFAOYSA-N
Smiles	CC(=O)NCCC1=CNC2=CC=CC=C12

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for N-Acetyltryptamine

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	ethanol	20.23	100
	DMSO	20.23	100

Preparing Stock Solutions for N-Acetyltryptamine

The following data is based on the product molecular weight 202.26.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	4.94 mL	24.72 mL	49.44 mL
5 mM	0.99 mL	4.94 mL	9.89 mL
10 mM	0.49 mL	2.47 mL	4.94 mL
50 mM	0.10 mL	0.49 mL	0.99 mL

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Reconstitution Calculator

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References for N-Acetyltryptamine

References are publications that support the biological activity of the product.

Dubocovich Melatonin receptors: are there multiple subtypes? TiPS 1995 PMID: 7762083
Thomas Arylalkylamine (serotonin) N-acetyl transferase assay using high-performance liquid-chromatography with fluorescence or electrochemical detection of N-acetyltryptamine. Anal.Biochem. 1990 PMID: 2327568
Dubocovich Luzindole (NO 774): a novel melatonin receptor antagonist. J.Pharmacol.Exp.Ther. 1988 PMID: 2843633
Dubocovich Characterization of a retinal melatonin receptor. J.Pharmacol.Exp.Ther. 1985 PMID: 2991499

Citations for N-Acetyltryptamine

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