N-Acetyltryptamine

Name: N -Acetyltryptamine
Brand: tocris
SKU: 0357

Catalog # 0357

Datasheet / COA / SDS

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Bio-Techne Corporation

tel: (800) 343-7475 (free phone)

tel: (612) 379-2956

customercare.na@bio-techne.com

Shipping Information

$35 to United States

Products in stock will be shipped in 1-3 business days unless specified.

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Key Product Details

Description:	Substrate for serotonin N-acetyl transferase
Purity:	≥99% (HPLC)
Molecular Weight:	202.26

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Biological Activity

N-Acetyltryptamine is a partial agonist for melatonin receptors in the retina. Also used for determination of serotonin N-acetyl transferase.

Compound Libraries

N-Acetyltryptamine is also offered as part of the Tocriscreen 2.0 Max. Find out more about compound libraries available from Tocris.

Technical Data

M. Wt	202.26
Formula	C₁₂H₁₄N₂O
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	1016-47-3
PubChem ID	70547
InChi Key	NVUGEQAEQJTCIX-UHFFFAOYSA-N
Smiles	CC(=O)NCCC1=CNC2=CC=CC=C12

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	ethanol	20.23	100
	DMSO	20.23	100

Preparing Stock Solutions

The following data is based on the product molecular weight 202.26.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	4.94 mL	24.72 mL	49.44 mL
5 mM	0.99 mL	4.94 mL	9.89 mL
10 mM	0.49 mL	2.47 mL	4.94 mL
50 mM	0.10 mL	0.49 mL	0.99 mL

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Reconstitution Calculator

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References

References are publications that support the biological activity of the product.

Dubocovich Characterization of a retinal melatonin receptor. J.Pharmacol.Exp.Ther. 1985 PMID: 2991499
Dubocovich Luzindole (NO 774): a novel melatonin receptor antagonist. J.Pharmacol.Exp.Ther. 1988 PMID: 2843633
Dubocovich Melatonin receptors: are there multiple subtypes? TiPS 1995 PMID: 7762083
Thomas Arylalkylamine (serotonin) N-acetyl transferase assay using high-performance liquid-chromatography with fluorescence or electrochemical detection of N-acetyltryptamine. Anal.Biochem. 1990 PMID: 2327568