N-(3-Oxododecanoyl)-L-homoserine lactone

Tocris Bioscience, part of Bio-Techne | Catalog # 6548

Bacterial quorum sensing autoinducer; immunomodulator
Discontinued Product
6548 has been discontinued. View all Immunosuppressants products.

Key Product Details

Description

Bacterial quorum sensing autoinducer; immunomodulator

View all Immunosuppressants »

Product Description

N-(3-Oxododecanoyl)-L-homoserine lactone is a bacterial quorum sensing signal molecule. Inhibits lymphocyte proliferation and TNF-α and IL-12 production by LPS-stimulated macrophages. Inhibits or promotes antibody production at high and low concentrations, respectively, in keyhole limpet hemocyanin (KLH)-stimulated spleen cells. Immunomodulator.

Product Specifications

Molecular Weight

297.39

Formula

C16H27NO4

Storage

Store at -20°C

Chemical Name

3-Oxo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]dodecanamide

CAS Number

168982-69-2

PubChem ID

3246941

InChI Key

PHSRRHGYXQCRPU-AWEZNQCLSA-N

SMILES

CCCCCCCCCC(CC(N[C@H]1CCOC1=O)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 29.74 100

Preparing Stock Solutions

The following data is based on the product molecular weight 297.39

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.36 mL 16.81 mL 33.63 mL
5 mM 0.67 mL 3.36 mL 6.73 mL
10 mM 0.34 mL 1.68 mL 3.36 mL
50 mM 0.07 mL 0.34 mL 0.67 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for N-(3-Oxododecanoyl)-L-homoserine lactone

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for N-(3-Oxododecanoyl)-L-homoserine lactone

For research use only

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