N-(3-Oxododecanoyl)-L-homoserine lactone

Name: N -(3-Oxododecanoyl)- L -homoserine lactone
Brand: Tocris Bioscience
SKU: 6548

Tocris Bioscience, part of Bio-Techne | Catalog # 6548

COA / SDS

Bacterial quorum sensing autoinducer; immunomodulator

Discontinued Product

6548 has been discontinued. View all Immunosuppressants products.

Key Product Details

Description:	Bacterial quorum sensing autoinducer; immunomodulator
Chemical Name:	3-Oxo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]dodecanamide
Molecular Weight:	297.39

View Full Technical Details for N-(3-Oxododecanoyl)-L-homoserine lactone

Technical Data
Citations

Biological Activity

N-(3-Oxododecanoyl)-L-homoserine lactone is a bacterial quorum sensing signal molecule. Inhibits lymphocyte proliferation and TNF-α and IL-12 production by LPS-stimulated macrophages. Inhibits or promotes antibody production at high and low concentrations, respectively, in keyhole limpet hemocyanin (KLH)-stimulated spleen cells. Immunomodulator.

Technical Data

M. Wt	297.39
Formula	C₁₆H₂₇NO₄
Storage	Store at -20°C
CAS Number	168982-69-2
PubChem ID	3246941
InChi Key	PHSRRHGYXQCRPU-AWEZNQCLSA-N
Smiles	CCCCCCCCCC(CC(N[C@H]1CCOC1=O)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References

References are publications that support the biological activity of the product.

Telford The Pseudomonas aeruginosa quorum-sensing signal molecule N-(3-oxododecanoyl)-L-homoserine lactone has immunomodulatory activity. Infect.Immun. 1998 PMID: 9423836

N-(3-Oxododecanoyl)-L-homoserine lactone

Tocris Bioscience, part of Bio-Techne | Catalog # 6548

Key Product Details

Biological Activity

Technical Data

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References

Product Documents

COA

Certificate of Analysis

SDS

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