MMPX

Name: MMPX
Brand: tocris
SKU: 0552

Catalog # 0552

Datasheet / COA / SDS

Discontinued Product

0552 has been discontinued. View all Phosphodiesterase Inhibitors products.

Order Information

Bio-Techne Corporation

tel: (800) 343-7475 (free phone)

tel: (612) 379-2956

customercare.na@bio-techne.com

Shipping Information

$35 to United States

Products in stock will be shipped in 1-3 business days unless specified.

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Key Product Details

Description:	PDE1 inhibitor
Chemical Name:	8-Methoxymethyl-3-isobutyl-1-methylxanthine
Molecular Weight:	266.3

View Full Technical Details for MMPX

Biological Activity

MMPX is a specific inhibitor of calmodulin-sensitive cyclic GMP phosphodiesterase (IC₅₀ = 5.2 μM).

Technical Data

M. Wt	266.3
Formula	C₁₂H₁₈N₄O₃
Storage	Store at RT
CAS Number	78033-08-6
PubChem ID	155806
InChi Key	NBLBCGUCPBXKOV-UHFFFAOYSA-N
Smiles	COCC1=NC2=C(N1)N(CC(C)C)C(=O)N(C)C2=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	ethanol		100

Preparing Stock Solutions

The following data is based on the product molecular weight 266.3.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.76 mL	18.78 mL	37.55 mL
5 mM	0.75 mL	3.76 mL	7.51 mL
10 mM	0.38 mL	1.88 mL	3.76 mL
50 mM	0.08 mL	0.38 mL	0.75 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

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Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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References

References are publications that support the biological activity of the product.

Wells and Mille Methylxanthine inhibitors of phosphodiesterases. Methods Enzymol. 1988 PMID: 2457788