ML 311

Tocris Bioscience, part of Bio-Techne | Catalog # 5733

Inhibits Mcl-1-BIM interaction
Discontinued Product
5733 has been discontinued. View all Bcl-2 Family Inhibitors products.

Key Product Details

Description

Inhibits Mcl-1-BIM interaction

View all Bcl-2 Family Inhibitors »

Product Description

ML 311 is an inhibits Mcl1-BIM interaction. Inhibits viability of Mcl1-dependent tumor cell lines. Induces cell death and decreased spheroid formation in Her2 positive breast cancer cells.

Product Specifications

Molecular Weight

415.45

Formula

C23H24F3N3O

Storage

Store at -20°C

Purity

≥99% (HPLC)

Chemical Name

7-[(4-Ethyl-1-piperazinyl)[4-(trifluoromethyl)phenyl]methyl]-8-quinolinol

CAS Number

315698-17-0

PubChem ID

3384730

InChI Key

NGAPBLRRJSKIRT-UHFFFAOYSA-N

SMILES

CCN(CC1)CCN1C(C2=CC=C(C(F)(F)F)C=C2)C3=C(O)C4=NC=CC=C4C=C3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 20.77 50
Ethanol 20.77 50

Preparing Stock Solutions for ML 311

The following data is based on the product molecular weight 415.45

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 4.81 mL 24.07 mL 48.14 mL
2.5 mM 0.96 mL 4.81 mL 9.63 mL
5 mM 0.48 mL 2.41 mL 4.81 mL
25 mM 0.10 mL 0.48 mL 0.96 mL

Calculators

Molarity Calculator

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for ML 311

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for ML 311

For research use only

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