MDL 72832 hydrochloride

Name: MDL 72832 hydrochloride
Brand: Tocris Bioscience
SKU: 0412

Tocris Bioscience a Bio-Techne Brand

Catalog # 0412

COA / SDS

Discontinued Product

0412 has been discontinued. View all 5-HT1A Receptor Ligands products.

Key Product Details

Description:	Potent 5-HT_1A ligand
Chemical Name:	8-[4-(1,4-Benzodioxan-2-ylmethylamino)butyl]-8-azaspiro[4.5]decane-7,9-dione hydrochloride
Purity:	≥99% (HPLC)
Molecular Weight:	422.95

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Biological Activity for MDL 72832 hydrochloride

MDL 72832 hydrochloride is a potent ligand at 5-HT_1A receptors, with mixed agonist and antagonist properties. An agonist at post-synaptic 5-HT_1A receptors.

Technical Data for MDL 72832 hydrochloride

M. Wt	422.95
Formula	C₂₂H₃₀N₂O₄.HCl
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	113777-40-5
PubChem ID	45073438
InChi Key	GQGDGISNRPBRSG-UHFFFAOYSA-N
Smiles	Cl.O=C1CC2(CCCC2)CC(=O)N1CCCCNCC1COC2=CC=CC=C2O1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for MDL 72832 hydrochloride

Solubility

Soluble Soluble to 5 mM in water

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References for MDL 72832 hydrochloride

References are publications that support the biological activity of the product.

Millan Induction of hypothermia as a model of 5-hydroxytryptamine_1A receptor-mediated activity in the rat - a pharmacological characterization of the actions of novel agonists and antagonists. J.Pharmacol.Exp.Ther. 1993 PMID: 8450471
Mir MDL 72832: a potent and stereoselective ligand at central and peripheral 5-HT_1A receptors. Eur.J.Pharmacol. 1988 PMID: 2840295

Citations for MDL 72832 hydrochloride

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