Malonoben

Name: Malonoben
Brand: tocris
SKU: 0479

Catalog # 0479

Datasheet / COA / SDS

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Bio-Techne Corporation

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$35 to United States

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Key Product Details

Description:	Oxidative phosphorylation uncoupler
Chemical Name:	3,5-Di-tert-butyl-4-hydroxybenzylidenemalononitrile
Molecular Weight:	282.38

View Full Technical Details for Malonoben

Biological Activity

Malonoben is a potent uncoupler of oxidative phosphorylation.

Technical Data

M. Wt	282.38
Formula	C₁₈H₂₂N₂O
Storage	Store at RT
CAS Number	10537-47-0
PubChem ID	16759147
InChi Key	MKUVGSJPVXTADZ-JYRVWZFOSA-N
Smiles	OC1=C(C(C)(C)C)C=C(\C=C(C#N)/[N+]#[C-])C=C1C(C)(C)C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	21.17	75

Preparing Stock Solutions

The following data is based on the product molecular weight 282.38.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.75 mM	4.72 mL	23.61 mL	47.22 mL
3.75 mM	0.94 mL	4.72 mL	9.44 mL
7.5 mM	0.47 mL	2.36 mL	4.72 mL
37.5 mM	0.09 mL	0.47 mL	0.94 mL

Molarity Calculator

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Reconstitution Calculator

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References

References are publications that support the biological activity of the product.

Muraoka and Terada 3,5-Di-tert-butyl-4-hydroxybenzylidemalonitrile: a new powerful uncoupler of respiratory-chain phosphorylation. Biochim.Biophys.Acta 1972 PMID: 4263281
Terada Some biochemical and physiochemical properties of the potent uncoupler SF 6847 hydroxybenzylidemalonitrile. Biochim.Biophys.Acta 1975 PMID: 237542
Terada The interaction of highly active uncouplers with mitochondria. Biochim.Biophys.Acta 1981 PMID: 7039674