KM 11060

Name: KM 11060
Brand: Tocris Bioscience
SKU: 3143

Tocris Bioscience, part of Bio-Techne | Catalog # 3143

Citations (8)

COA / SDS

Corrects F508del-CFTR trafficking

Discontinued Product

3143 has been discontinued. View all Other CFTR Compounds products.

Key Product Details

Description:	Corrects F508del-CFTR trafficking
Chemical Name:	7-Chloro-4-[4-[4-chlorophenyl)sulfonyl]-1-piperazinyl]quinoline
Purity:	≥98% (HPLC)
Molecular Weight:	422.33

View Full Technical Details for KM 11060

Technical Data
Citations

Biological Activity for KM 11060

KM 11060 is a corrects F508del-CFTR trafficking; increases the amount of functional CFTR at the plasma membrane (~75%). Shown to inhibit PDE5 activity.

Technical Data for KM 11060

M. Wt	422.33
Formula	C₁₉H₁₇Cl₂N₃O₂S
Storage	Store at RT
Purity	≥98% (HPLC)
CAS Number	774549-97-2
PubChem ID	1241327
InChi Key	GIEHIZKCIZLXLF-UHFFFAOYSA-N
Smiles	ClC(C=C4)=CC=C4S(N(CC3)CCN3C1=CC=NC2=C1C=CC(Cl)=C2)(=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for KM 11060

References are publications that support the biological activity of the product.

Robert Structural analog of silde. identified as a novel corrector of the F508del-CFTR trafficking defect. Mol.Pharmacol. 2008 PMID: 17975008

KM 11060

Tocris Bioscience, part of Bio-Techne | Catalog # 3143

Key Product Details

Biological Activity for KM 11060

Technical Data for KM 11060

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for KM 11060

Product Documents for KM 11060

COA

Certificate of Analysis

SDS

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