IDRA 21

Biological Activity for IDRA 21

Technical Data for IDRA 21

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References for IDRA 21

References are publications that support the biological activity of the product.

• Thompson 7-Chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine S,S-dioxide (IDRA 21), a congener of aniracetam, potently abates pharmacologically induced cognitive impairments in patas monkeys. Proc.Natl.Acad.Sci.U.S.A. 1995 PMID: 7644474
• Zivkovic 7-Chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine S,S-dioxide (IDRA 21): a benzothiadiazine derivative that enhances cognition by attenuating DL-α-amino-2,3-dihydro-5-methyl-3-oxo-4-isoxazolepropanoic acid (AMPA) receptor desensitization. J.Pharmacol.Exp.Ther. 1995 PMID: 7815345
• Impagnatiello 7-Chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine S,S-dioxide: a partial modulator of AMPA receptor desensitization devoid of neurotoxicity. Proc.Natl.Acad.Sci.U.S.A. 1997 PMID: 9192690