ICI 182,780

Citations are publications that use Bio-Techne products. Selected citations for ICI 182,780 include:

• Cortes et al. (2019) GPER is a mechanoregulator of pancreatic stellate cells and the tumor microenvironment. EMBO Rep. 20
  PMID: 30538117
• Cortes et al. (2019) TAX mechanically reprograms the tumor microenvironment via HIF-1A and reduces cancer cell survival. EMBO Rep. 20
  PMID: 30538116
• Cortes et al. (2019) TAX mechanically deactivates hepatic stellate cells via the G protein-coupled estrogen receptor. Oncogene. 38:2910
  PMID: 30575816
• Kasonga et al. (2019) Data on UPLC/MS method validation for the biodegradation of pharmaceuticals and intermediates by a fungal consortium and on T47DK-Bluc reporter gene assay to assess the reduction of their estrogenic activity. Data Brief. 25:104336
  PMID: 31453302
• Hosford et al. (2019) Estrogen therapy induces an unfolded protein response to drive cell death in ER+ breast cancer. Mol Oncol. 13:1778
  PMID: 31180176
• Rincó n-Rodriguez et al. (2019) F-Spondin Is the Signal by Which 2-Methoxyestradiol Induces Apoptosis in the Endometrial Cancer Cell Line Ishikawa. Int J Mol Sci. 20
  PMID: 31394756
• Bloomfield and Louie (2019) Chronic cadmium exposure decreases the dependency of MCF7 breast cancer cells on ERα. Sci Rep. 9:12135
  PMID: 31431634
• Demas et al. (2019) Glutamine Metabolism Drives Growth in Advanced Hormone Receptor Positive Breast Cancer. Front Oncol. 9:686
  PMID: 31428575
• Ulhaq and Kishida (2018) Brain Aromatase Modulates Serotonergic Neuron by Regulating Serotonin Levels in Zebrafish Embryos and Larvae. Front Endocrinol (Lausanne). 9:230
  PMID: 29867763
• Kaymak et al. (2018) Role for the transcriptional activator ZRF1 in early metastatic events in breast cancer progression and endocrine resistance. Oncotarget. 9:28666
  PMID: 29983888
• Du et al. (2018) Key regulators of lipid metabolism drive endocrine resistance in invasive lobular breast cancer. Breast Cancer Res. 20:106
  PMID: 30180878
• Simões et al. (2018) Estrogenicity of essential oils is not required to relieve symptoms of urogenital atrophy in breast cancer survivors. Ther Adv Med Oncol. 10:1758835918766180
  PMID: 29636827
• Rabaglino et al. (2018) A transcriptomics model of estrogen action in the ovine fetal hypothalamus: evidence for estrogenic effects of ICI 182,780. Physiol Rep. 6:e13871
  PMID: 30221477
• Li et al. (2018) Upregulation of IRS1 Enhances IGF1 Response in Y537S and D538G ESR1 Mutant Breast Cancer Cells. Endocrinology. 159:285
  PMID: 29029116
• Gibson et al. (2018) The impact of 27-hydroxycholesterol on endometrial cancer proliferation. Endocr Relat Cancer. 25:381
  PMID: 29371332
• Jallow et al. (2018) 17β-Estradiol and ICI182,780 Differentially Regulate STAT5 Isoforms in Female Mammary Epithelium, With Distinct Outcomes. J Endocr Soc. 2:293
  PMID: 29594259
• Zhu (2017) Differential and directional estrogenic signaling pathways induced by enterolignans and their precursors. PLoS One. 12(2):e0171390
  PMID: 28152041
• Lou et al. (2017) OE Suppresses TLR4-triggered Apoptosis of Decidual Stromal Cells and Drives an Anti-inflammatory TH2 Shift by Activating SGK1. Int J Biol Sci. 13:434
  PMID: 28529452
• Lu et al. (2017) Estrogen enhances mismatch repair by induction of MLH1 expression via estrogen receptor-β. Oncotarget. 8:38767
  PMID: 28404976
• Panza et al. (2017) E2 via estrogen receptor beta influences ROS levels through the transcriptional regulation of SIRT3 in human seminoma TCam-2 cells. Tumour Biol. 39:1010428317701640
  PMID: 28459202
• Stender (2017) Structural and molecular mechanisms of cytokine-mediated endocrine resistance in human breast cancer cells. Mol Cell. 65(6):1122
  PMID: 28306507
• Wong et al. (2017) Role of inducible nitric oxide synthase in endothelium-independent relaxation to RLX in rat aorta. Br J Pharmacol. 174:718
  PMID: 28138957
• Diep et al. (2016) Progesterone induces progesterone receptor gene (PGR) expression via rapid activation of protein kinase pathways required for cooperative estrogen receptor alpha (ER) and progesterone receptor (PR) genomic action at ER/PR target genes. Steroids. 114:48
  PMID: 27641443
• Peretz et al. (2016) Estrogenic compounds reduce influenza A virus replication in primary human nasal epithelial cells derived from female, but not male, donors. Am J Physiol Lung Cell Mol Physiol. 310:L415
  PMID: 26684252
• Gupta et al. (2016) NCOA3 coactivator is a transcriptional target of XBP1 and regulates PERK-eIF2α-ATF4 signalling in breast cancer. Oncogene. 35:5860
  PMID: 27109102
• Pastore et al. (2016) Identification of Differential ER-Alpha Versus ER-Beta Mediated Activation of eNOS in Ovine Uterine Artery Endothelial Cells. Biol Reprod. 94:139
  PMID: 27170438
• Ciucci et al. (2016) Multiple direct and indirect mechanisms drive estrogen-induced tumor growth in high grade serous ovarian cancers. Oncotarget. 7:8155
  PMID: 26797759
• Mao et al. (2016) Antiestrogen resistant cell lines expressing estrogen receptor α mutations upregulate the unfolded protein response and are killed by BHPI Scientific Reports. 6:34753
  PMID: 27713477
• Bains and Roberts (2016) Estrogen protects against DA neuron toxicity in primary mesencephalic cultures through an indirect P13K/Akt mediated astrocyte pathway. Neurosci Lett. 610:79
  PMID: 26520464
• Maselli et al. (2016) Low expression of estrogen receptor β in T lymphocytes and high serum levels of anti-estrogen receptor α antibodies impact disease activity in female patients with systemic lupus erythematosus. Front Vet Sci. 7:3
  PMID: 26759713
• Xu et al. (2015) A short report: PAMM, a novel antioxidant protein, induced by oxidative stress. Redox Biol. 6:446
  PMID: 26402163
• Kastrati et al. (2015) PHLDA1 expression is controlled by an estrogen receptor-NFκB-miR-181 regulatory loop and is essential for formation of ER+ mammospheres. Oncogene. 34:2309
  PMID: 24954507
• Wardell et al. (2015) Evaluation of the pharmacological activities of RAD1901, a selective estrogen receptor degrader. Endocr Relat Cancer. 22:713
  PMID: 26162914
• Larsen et al. (2015) Aurora kinase B is important for antiestrogen resistant cell growth and a potential biomarker for tamox. resistant breast cancer. Aging Cell. 15:239
  PMID: 25885472
• Xiong et al. (2015) Opposite effects of two estrogen receptors on tau phosphorylation through disparate effects on the miR-218/PTPA pathway. Breast Cancer Res Treat. 14:867
  PMID: 26111662
• Bean et al. (2015) The PI3K/mTOR dual inhibitor P7170 demonstrates potent activity against endocrine-sensitive and endocrine-resistant ER+ breast cancer. Oncotarget. 149:69
  PMID: 25491778
• Luzhna et al. (2015) Altered radiation responses of breast cancer cells resistant to hormonal therapy. Mol Cell Biol. 6:1678
  PMID: 25682200
• Albanito et al. (2015) Effects of Atrazine on Estrogen Receptor α- and G Protein-Coupled Receptor 30-Mediated Signaling and Proliferation in Cancer Cells and Cancer-Associated Fibroblasts. Environ Health Perspect. 123:493
  PMID: 25616260
• Segovia-Mendoza et al. (2015) Antihormonal agents as a strategy to improve the effect of chemo-radiation in cervical cancer: in vitro and in vivo study. J Biol Chem. 15:21
  PMID: 25622528
• Wang et al. (2015) Differential effects of estrogen and estrogen receptor antagonist, ICI 182 780, on the expression of calbindin-D9k in rat pituitary prolactinoma GH3 cells. Cancer Cell Int. 7:8498
  PMID: 25674214
• Myers et al. (2015) Estrogenic and anti-estrogenic activity of off-the-shelf hair and skin care products. BMC Cancer. 25:271
  PMID: 24849798
• Hu et al. (2015) NF-κB signaling is required for XBP1 (unspliced and spliced)-mediated effects on antiestrogen responsiveness and cell fate decisions in breast cancer. Oncogenesis. 35:379
  PMID: 25368386
• Harvey et al. (2015) Methoxychlor and its metabolite HPTE inhibit cAMP production and expression of estrogen receptors α and β in the rat granulosa cell in vitro. Reprod Toxicol. 51:72
  PMID: 25549949
• Kim et al. (2015) Estrogen promotes luteolysis by redistributing prostaglandin F2α receptors within primate luteal cells. Reproduction. 149:453
  PMID: 25687410
• Miyoshi et al. (2015) Nodes-and-connections RNAi knockdown screening: identification of a signaling molecule network involved in fulves. action and breast cancer prognosis. Biol Sex Differ. 4:e172
  PMID: 26479444
• Shappell et al. (2015) The Effects of Steroid Implant and Dietary Soybean Hulls on Estrogenic Activity of Sera of Steers Grazing Toxic Endophyte-Infected Tall Fescue Pasture. Cancer Lett. 2:30
  PMID: 26664959
• Zhou et al. (2015) Estrogen mediated expression of nucleophosmin 1 in human endometrial carcinoma clinical stages through estrogen receptor-α signaling. Endocrinology. 14:540
  PMID: 25663821
• Hole et al. (2015) New cell culture model for aromatase inhibitor-resistant breast cancer shows sensitivity to fulves. treatment and cross-resistance between letr. and exeme. BMC Cancer. 46:1481
  PMID: 25625755
• Tozzi et al. (2015) Endogenous 17β-OE is required for activity-dependent long-term potentiation in the striatum: interaction with the DArgic system. Front Cell Neurosci. 9:192
  PMID: 26074768
• Tomita et al. (2015) A cluster of noncoding RNAs activates the ESR1 locus during breast cancer adaptation. Nat Commun. 6:6966
  PMID: 25923108
• Simões et al. (2015) Anti-estrogen Resistance in Human Breast Tumors Is Driven by JAG1-NOTCH4-Dependent Cancer Stem Cell Activity. Cell Cycle. 12:1968
  PMID: 26387946
• Castro et al. (2015) Differential expression of upstream stimulatory factor (USF) 2 variants in eutopic endometria from women with endometriosis: OE regulation. Biol Res. 48:56
  PMID: 26453052
• Wu et al. (2015) Effects of estrogen on growth and smooth muscle differentiation of vascular wall-resident CD34(+) stem/progenitor cells. Atherosclerosis. 240:453
  PMID: 25898000
• Adomas et al. (2014) Breast tumor specific mutation in GATA3 affects physiological mechanisms regulating transcription factor turnover. BMC Cancer. 14:278
  PMID: 24758297
• Choi et al. (2014) Suppression of autophagic activation in the mouse uterus by estrogen and progesterone. Cell Rep. 221:39
  PMID: 24443716
• Fan et al. (2014) A molecular model for the mechanism of acquired tamox. resistance in breast cancer. Eur J Cancer. 50:2866
  PMID: 25204804
• Giretti et al. (2014) Effects of Estetrol on Migration and Invasion in T47-D Breast Cancer Cells through the Actin Cytoskeleton. Front Endocrinol (Lausanne). 5:80
  PMID: 24904530
• Yi et al. (2014) Anti-tumor efficacy of fulves. in estrogen receptor positive gastric cancer. Sci Rep. 4:7592
  PMID: 25534230
• Gottardo et al. (2014) Antiapoptotic factor humanin is expressed in normal and tumoral pituitary cells and protects them from TNF-α-induced apoptosis. PLoS One. 9:e111548
  PMID: 25360890
• Yonova et al. (2014) Diaryl and heteroaryl sulfides: synthesis via sulfenyl chlorides and evaluation as selective anti-breast-cancer agents. J Org Chem. 79:1947
  PMID: 24564865
• Alao et al. (2014) Selective inhibition of RET mediated cell proliferation in vitro by the kinase inhibitor SPP86. BMC Cancer. 14:853
  PMID: 25409876
• Haagenson et al. (2014) Functional analysis of MKP-1 and MKP-2 in breast cancer tamox. sensitivity. Oncotarget. 5:1101
  PMID: 24658355
• Fan et al. (2014) Inhibition of c-Src blocks oestrogen-induced apoptosis and restores oestrogen-stimulated growth in long-term oestrogen-deprived breast cancer cells. Eur J Cancer. 50:457
  PMID: 24183378
• Speroni et al. (2014) Hormonal regulation of epithelial organization in a three-dimensional breast tissue culture model. PLoS One. 20:42
  PMID: 23675751
• Colciago et al. (2014) In vitro chronic administration of ERbeta selective ligands and prostate cancer cell growth: hypotheses on the selective role of 3beta-adiol in AR-positive RV1 cells. Biomed Res Int. 2014:801473
  PMID: 24877132
• Nag and Mokha (2014) Activation of a Gq-coupled membrane estrogen receptor rapidly attenuates α2-adrenoceptor-induced antinociception via an ERK I/II-dependent, non-genomic mechanism in the female rat. Am J Physiol Regul Integr Comp Physiol. 267:122
  PMID: 24613724
• Cook and Clarke (2014) Estrogen receptor-α signaling and localization regulates autophagy and unfolded protein response activation in ER+ breast cancer. Steroids. 1
  PMID: 26005699
• Jafaar et al. (2014) β-D-glucan inhibits endocrine-resistant breast cancer cell proliferation and alters gene expression. Int J Oncol. 44:1365
  PMID: 24534923
• Liang et al. (2014) Egr1 protein acts downstream of estrogen-leukemia inhibitory factor (LIF)-STAT3 pathway and plays a role during implantation through targeting Wnt4. J Biol Chem. 289:23534
  PMID: 25012664
• Oróstica et al. (2014) OE increases cAMP in the oviductal secretory cells through a nongenomic mechanism. Reproduction. 148:285
  PMID: 25038866
• Hill and Muldrew (2014) Oestrogen upregulates the sarcoplasmic reticulum Ca(2+) ATPase pump in coronary arteries. Clin Exp Pharmacol Physiol. 41:430
  PMID: 24684418
• Seo et al. (2014) Comprehensive analysis of prostaglandin metabolic enzyme expression during pregnancy and the characterization of AKR1B1 as a prostaglandin F synthase at the maternal-conceptus interface in pigs. Breast Cancer Res. 90:99
  PMID: 24695626
• Sievers et al. (2013) Differential action of monohydroxylated polycyclic aromatic hydrocarbons with estrogen receptors α and β. Proc Natl Acad Sci U S A. 132:359
  PMID: 22989670
• Aida-Yasuoka et al. (2013) OE promotes the development of a fibrotic phenotype and is increased in the serum of patients with systemic sclerosis. J Neurosci. 15:R10
  PMID: 23305385
• Aupperlee et al. (2013) Amphiregulin mediates progesterone-induced mammary ductal development during puberty. J Neurosci. 15:R44
  PMID: 23705924
• Teng et al. (2013) Endocrine disruptors fludioxonil and fenhexamid stimulate miR-21 expression in breast cancer cells. Toxicol Sci. 131:71
  PMID: 23052036
• Johansson et al. (2013) Retinoic acid receptor alpha is associated with tamox. resistance in breast cancer. Nat Commun. 4:2175
  PMID: 23868472
• Varea et al. (2013) OOE signalling through the Akt-mTORC1-S6K1. Biochim Biophys Acta. 1833:1052
  PMID: 23295457
• Greaves et al. (2013) ERβ-dependent effects on uterine endothelial cells are cell specific and mediated via Sp1. Hum Reprod. 28:2490
  PMID: 23756706
• Spink et al. (2013) Expression of the aryl hydrocarbon receptor is not required for the proliferation, migration, invasion, or estrogen-dependent tumorigenesis of MCF-7 breast cancer cells. Mol Carcinog. 52:544
  PMID: 22388733
• Giordano et al. (2013) Gender differences in brain susceptibility to oxidative stress are mediated by levels of paraoxonase-2 expression. Free Radic Biol Med. 58:98
  PMID: 23376469
• Smith et al. (2013) The membrane estrogen receptor ligand STX rapidly enhances GABAergic signaling in NPY/AgRP neurons: role in mediating the anorexigenic effects of 17β-OE. Am J Physiol Endocrinol Metab. 305:E632
  PMID: 23820624
• Morandi et al. (2013) GDNF-RET signaling in ER-positive breast cancers is a key determinant of response and resistance to aromatase inhibitors. Cancer Res. 73:3783
  PMID: 23650283
• Zhang et al. (2013) Fulvestrant regulates epidermal growth factor (EGF) family ligands to activate EGF receptor (EGFR) signaling in breast cancer cells. Environ Health Perspect. 139:351
  PMID: 23686416
• Ruiz et al. (2013) Induction of hepatic multidrug resistance-associated protein 3 by ethynylOE is independent of cholestasis and mediated by estrogen receptor. Proc Natl Acad Sci U S A. 41:275
  PMID: 23077105
• Kim et al. (2013) The effect of estrogen compounds on human embryoid bodies. Proc Natl Acad Sci U S A. 20:661
  PMID: 23184660
• Peretz et al. (2012) Bisphenol A inhibits follicle growth and induces atresia in cultured mouse antral follicles independently of the genomic estrogenic pathway. Biol Reprod. 87:63
  PMID: 22743301
• Leal et al. (2012) p130Cas over-expression impairs mammary branching morphogenesis in response to estrogen and EGF. PLoS One. 7:e49817
  PMID: 23239970
• Niu et al. (2012) Effects of gonadal hormones on the peripheral cannabinoid receptor 1 (CB1R) system under a myositis condition in rats. J Cereb Blood Flow Metab. 153:2283
  PMID: 22940464
• Collins-Burow et al. (2012) Antiestrogenic activity of flavonoid phytochemicals mediated via the c-Jun N-terminal protein kinase pathway. Cell-type specific regulation of estrogen receptor alpha. J Steroid Biochem Mol Biol. 132:186
  PMID: 22634477
• Shim and Lee (2012) Estrogen receptor is activated by korean red ginseng in vitro but not in vivo. J Ginseng Res. 36:169
  PMID: 23717117
• Mahmoodzadeh et al. (2012) 17β-OE-induced interaction of ERα with NPPA regulates gene expression in cardiomyocytes. Cardiovasc Res. 96:411
  PMID: 22962310
• Vinnedge et al. (2012) The DEK oncogene is a target of steroid hormone receptor signaling in breast cancer. Neuroscience. 7:e46985
  PMID: 23071688
• Guido et al. (2012) Estrogen receptor β (ERβ) produces autophagy and necroptosis in human seminoma cell line through the binding of the Sp1 on the phosphatase and tensin homolog deleted from chromosome 10 (PTEN) promoter gene. Int J Clin Exp Pathol. 11:2911
  PMID: 22810004
• Zuloaga et al. (2012) Estrogen receptor β dependent attenuation of cytokine-induced cyclooxygenase-2 by androgens in human brain vascular smooth muscle cells and rat mesenteric arteries. Exp Neurol. 77:835
  PMID: 22542504
• Rodriguez-Ubreva et al. (2012) Pre-B cell to macrophage transdifferentiation without significant promoter DNA methylation changes. Nucleic Acids Res. 40:1954
  PMID: 22086955
• Cook et al. (2012) Glucose-regulated protein 78 controls cross-talk between apoptosis and autophagy to determine antiestrogen responsiveness. Int J Mol Sci. 72:3337
  PMID: 22752300
• Lee et al. (2012) Estrogen-like activity of aqueous extract from Agrimonia pilosa Ledeb. in MCF-7 cells. Endocrinology. 12:260
  PMID: 23259680
• Park et al. (2012) Activation of Estrogen Receptor by Bavachin from Psoralea corylifolia. Proc Natl Acad Sci U S A. 20:183
  PMID: 24116293
• Richardson et al. (2012) Estrogen prevents oxidative damage to the mitochondria in Friedreich's ataxia skin fibroblasts. Endocrinology. 7:e34600
  PMID: 22509330
• Brion et al. (2012) Screening estrogenic activities of chemicals or mixtures in vivo using transgenic (cyp19a1b-GFP) zebrafish embryos. PLoS One. 7:e36069
  PMID: 22586461
• Zhang et al. (2012) Estrogen-responsive nitroso-proteome in uterine artery endothelial cells: role of endothelial nitric oxide synthase and estrogen receptor-β. J Cell Physiol. 227:146
  PMID: 21374595
• Bobustuc et al. (2012) MGMT inhibition restores ERα functional sensitivity to antiestrogen therapy. Mol Med. 18:913
  PMID: 22549111
• González-Arenas et al. (2012) OE increases cell growth in human astrocytoma cell lines through ERα activation and its interaction with SRC-1 and SRC-3 coactivators. Biochim Biophys Acta. 1823:379
  PMID: 22142990
• Wen et al. (2012) Modulation of ovine SBD-1 expression by 17beta-OE in ovine oviduct epithelial cells. BMC Vet Res. 8:143
  PMID: 22920556
• Babu et al. (2012) Genistein prevents hyperglycemia-induced monocyte adhesion to human aortic endothelial cells through preservation of the cAMP signaling pathway and ameliorates vascular inflammation in obese diabetic mice. J Nutr. 142:724
  PMID: 22399524
• Youn et al. (2012) Inhibition of XO or NOX attenuates diethylstilbestrol-induced endothelial nitric oxide deficiency without affecting its effects on LNCaP cell invasion and apoptosis. Clin Sci (Lond). 123:509
  PMID: 22568671
• Ropero et al. (2012) Insotropic effect of the non-steroidal compound STX in pancreatic β-cells. PLoS One. 7:e34650
  PMID: 22506040
• Antoon et al. (2012) Inhibition of p38-MAPK alters SRC coactivation and estrogen receptor phosphorylation. Cancer Biol Ther. 13:1026
  PMID: 22825349
• Cao et al. (2012) Estrogen receptor β activation is antinociceptive in a model of visceral pain in the rat. J Pain. 13:685
  PMID: 22698981
• Wang and Kuehl-Kovarik (2012) OE directly attenuates sodium currents and depolarizing afterpotentials in isolated gonadotropin-releasing hormone neurons. Brain Res. 1436:81
  PMID: 22209345
• Hsu et al. (2011) JNK suppression is essential for 17β-OE inhibits prostaglandin E2-Induced uPA and MMP-9 expressions and cell migration in human LoVo colon cancer cells. J Vet Sci. 18:61
  PMID: 21859479
• Ahn et al. (2011) Expression and regulation of Enpp2 in rat uterus during the estrous cycle. Toxicol Sci. 12:379
  PMID: 22122904
• Baquié et al. (2011) The liver receptor homolog-1 (LRH-1) is expressed in human islets and protects {β}-cells against stress-induced apoptosis. FEMS Immunol Med Microbiol. 20:2823
  PMID: 21536586
• Tyagi et al. (2011) Daidzein prevents the increase in CD4+CD28null T cells and B lymphopoesis in ovariectomized mice: a key mechanism for anti-osteoclastogenic effect. PLoS One. 6:e21216
  PMID: 21731677
• Liu et al. (2011) Spinal synthesis of estrogen and concomitant signaling by membrane estrogen receptors regulate spinal κ- and μ-opioid receptor heterodimerization and female-specific spinal mor. antinociception. J Neurosci. 31:11836
  PMID: 21849544
• Ivanova et al. (2011) Tamoxifen increases nuclear respiratory factor 1 transcription by activating estrogen receptor beta and AP-1 recruitment to adjacent promoter binding sites. FASEB J. 25:1402
  PMID: 21233487
• Yu et al. (2011) mTOR controls ovarian follicle growth by regulating granulosa cell proliferation. PLoS One. 6:e21415
  PMID: 21750711
• Richardson et al. (2011) Estrogen protection in Friedreich's ataxia skin fibroblasts. Endocrinology. 152:2742
  PMID: 21540287
• Zheng et al. (2011) 17β-OE enhances breast cancer cell motility and invasion via extra-nuclear activation of actin-binding protein ezrin. PLoS One. 6:e22439
  PMID: 21818323
• He et al. (2011) Complete estrogen receptor blocker ICI182,780 promotes the proliferation of vascular smooth muscle cells. Acta Biochim Biophys Sin (Shanghai). 43:118
  PMID: 21193431
• Shanle et al. (2011) Generation of stable reporter breast cancer cell lines for the identification of ER subtype selective ligands. Biochem Pharmacol. 82:1940
  PMID: 21924251
• Burns et al. (2011) Selective mutations in estrogen receptor alpha D-domain alters nuclear translocation and non-estrogen response element gene regulatory mechanisms. J Biol Chem. 286:12640
  PMID: 21285458
• Lappano et al. (2011) The cholesterol metabolite 25-hydroxycholesterol activates estrogen receptor α-mediated signaling in cancer cells and in cardiomyocytes. PLoS One. 6:e16631
  PMID: 21304949
• Thangavel et al. (2011) Therapeutically activating RB: reestablishing cell cycle control in endocrine therapy-resistant breast cancer. Endocr Relat Cancer. 18:333
  PMID: 21367843
• Corcoran et al. (2011) The effect of 17β-OE on cholesterol content in human macrophages is influenced by the lipoprotein milieu. Clin Cancer Res. 47:109
  PMID: 21830321
• Okada et al. (2010) Estrogen stimulates proliferation and differentiation of neural stem/progenitor cells through different signal transduction pathways. Am J Physiol Heart Circ Physiol. 11:4114
  PMID: 21152324
• Raffetto et al. (2010) Estrogen receptor-mediated enhancement of venous relaxation in female rat: implications in sex-related differences in varicose veins. J Vasc Surg. 51:972
  PMID: 20347696
• Cruz et al. (2010) Proliferation of human mammary cancer cells exposed to 27-hydroxycholesterol. J Expo Sci Environ Epidemiol. 1:531
  PMID: 22993572
• Son et al. (2010) Androgen receptor-dependent transactivation of growth arrest-specific gene 6 mediates inhibitory effects of testost. on vascular calcification. J Biol Chem. 285:7537
  PMID: 20048160
• Bender et al. (2010) Roles of 17β-OE involve regulation of reelin expression and synaptogenesis in the dentate gyrus. Cereb Cortex. 20:2985
  PMID: 20421250
• Peng et al. (2010) Unexpected hormonal activity of a catechol equine estrogen metabolite reveals reversible glutathione conjugation. Chem Res Toxicol. 23:1374
  PMID: 20540524
• Suzuki et al. (2010) Down-regulation of PROS1 gene expression by 17beta-OE via estrogen receptor alpha (ERalpha)-Sp1 interaction recruiting receptor-interacting protein 140 and the corepressor-HDAC3 complex. J Biol Chem. 285:13444
  PMID: 20200160
• Rasmussen et al. (2010) Prolactin and oestrogen synergistically regulate gene expression and proliferation of breast cancer cells. Endocr Relat Cancer. 17:809
  PMID: 20601496
• Harte et al. (2010) BRD7, a subunit of SWI/SNF complexes, binds directly to BRCA1 and regulates BRCA1-dependent transcription. Cancer Res. 70:2538
  PMID: 20215511
• Allard and Colaiácovo (2010) Bisphenol A impairs the double-strand break repair machinery in the germline and causes chromosome abnormalities. Proc Natl Acad Sci U S A. 107:20405
  PMID: 21059909
• Thuillier et al. (2010) Interdependence of platelet-derived growth factor and estrogen-signaling pathways in inducing neonatal rat testicular gonocytes proliferation. Biol Reprod. 82:825
  PMID: 20089883
• Rangasamy et al. (2010) Estrogen suppresses MLK3-mediated apoptosis sensitivity in ER+ breast cancer cells. Cancer Res. 70:1731
  PMID: 20145118
• Wang et al. (2010) Estrogen receptor α (ERα) mediates 17β-OE (E2)-activated expression of HBO1. Proc Natl Acad Sci U S A. 29:140
  PMID: 21040551
• Zhang (2010) Hepatocyte growth factor system in the mouse uterus: variation across the estrous cycle and regulation by 17-β-OE and progesterone. Clin Cancer Res. 82:1037
  PMID: 20147731
• Sobrino et al. (2010) OE selectively stimulates endothelial prostacyclin production through estrogen receptor-{alpha}. J Mol Endocrinol. 44:237
  PMID: 20110403
• Yang et al. (2010) Extranuclear estrogen receptors mediate the neuroprotective effects of estrogen in the rat hippocampus. PLoS One. 5:e9851
  PMID: 20479872
• Mahmoodzadeh et al. (2010) 17beta-OE inhibits matrix metalloproteinase-2 transcription via MAP kinase in fibroblasts. Cardiovasc Res. 85:719
  PMID: 19861308
• Dalvai and Bystricky (2010) Cell cycle and anti-estrogen effects synergize to regulate cell proliferation and ER target gene expression. PLoS One. 5:e11011
  PMID: 20543978
• Antoon et al. (2010) Antiestrogenic effects of the novel sphingosine kinase-2 inhibitor ABC294640. Endocrinology. 151:5124
  PMID: 20861237
• Foong et al. (2010) 5-HT(1A), SST(1), and SST(2) receptors mediate inhibitory postsynaptic potentials in the submucous plexus of the guinea pig ileum. Receptors Clin Investig. 298:G384
  PMID: 20007849
• Ma et al. (2010) Gender-specific reduction in contraction is associated with increased estrogen receptor expression in single vascular smooth muscle cells of female rat. Cell Physiol Biochem. 26:457
  PMID: 20798531
• Sanchez et al. (2010) Estrogen receptor-alpha promotes breast cancer cell motility and invasion via focal adhesion kinase and N-WASP. Mol Endocrinol. 24:2114
  PMID: 20880986
• Murphy et al. (2010) OE suppresses NF-kappa B activation through coordinated regulation of let-7a and miR-125b in primary human macrophages. J Immunol. 184:5029
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• LaPensee et al. (2010) Bisphenol A and OE are equipotent in antagonizing cisplatin-induced cytotoxicity in breast cancer cells. Cancer Res. 290:167
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• Used on human primary mammary epithelial cells

  Name: Anonymous
  Species: Human
  Assay Type: In Vitro
  Cell Line/Tissue: Human Primary Mammary Epithelial Cells
  This product was dissolved in ethanol and delivered to human primary mammary epithelial cells in vitro.

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