Hexamethonium bromide

Name: Hexamethonium bromide
Brand: Tocris Bioscience
SKU: 4111
Rating: 5 (1 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 4111

(1)

Citations (8)

COA / SDS

Non-competitive nAChR antagonist

Discontinued Product

4111 has been discontinued. View all Additional Nicotinic Receptor Antagonists products.

Key Product Details

Description:	Non-competitive nAChR antagonist
Chemical Name:	N,N,N,N',N',N'-Hexamethylhexamethylenediammonium dibromide
Molecular Weight:	362.19

View Full Technical Details for Hexamethonium bromide

Technical Data
Citations / Reviews (1)

Biological Activity for Hexamethonium bromide

Hexamethonium bromide is a nicotinic receptor (nAChR) blocker at autonomic ganglia; prevents nicotine-mediated inhibition of apoptosis. Induces changes in neuronal activity similar to the influences of glutamate in vitro. Inhibits nicotine-mediated induction of XIAP and survivin.

Technical Data for Hexamethonium bromide

M. Wt	362.19
Formula	C₁₂H₃₀Br₂N₂
Storage	Desiccate at RT
CAS Number	55-97-0
PubChem ID	5938
InChi Key	FAPSXSAPXXJTOU-UHFFFAOYSA-L
Smiles	C[N+](C)(C)CCCCCC[N+](C)(C)C.[Br-].[Br-]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for Hexamethonium bromide

References are publications that support the biological activity of the product.

Dasgupta Nicotine inhibits apoptosiis induced by chemotherapeutic drugs by up-regulating XIAP and survivin. Proc.Natl.Acad.Sci.
Karavaev The nicotinic receptor blocker hexamethonium alters neuronal responses to glutamate in the medial septal area of the brain of the ground squirrel in vitro. Neurosci.Behav.Physiol. 2008 PMID: 18264777

Hexamethonium bromide

Tocris Bioscience, part of Bio-Techne | Catalog # 4111

Key Product Details

Biological Activity for Hexamethonium bromide

Technical Data for Hexamethonium bromide

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for Hexamethonium bromide

Product Documents for Hexamethonium bromide

COA

Certificate of Analysis

SDS

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