GR 46611

Name: GR 46611
Brand: Tocris Bioscience
SKU: 0864

Tocris Bioscience, part of Bio-Techne | Catalog # 0864

Citations (1)

COA / SDS

5-HT1D agonist

Discontinued Product

0864 has been discontinued. View all 5-HT1D Receptor Agonists products.

Key Product Details

Description:	5-HT_1D agonist
Chemical Name:	3-[3-(2-Dimethylaminoethyl)-1H-indol-5-yl]-N-(4-methoxybenzyl)acrylamide
Molecular Weight:	377.49

View Full Technical Details for GR 46611

Technical Data
Citations

Biological Activity for GR 46611

GR 46611 is a 5-HT_1D receptor agonist. Blockade of GR 46611-induced hypothermia in the guinea pig provides a useful model with which to study the potency and duration of action of centrally acting 5-HT_1D receptor ligands.

Licensing Information

Sold with the permission of GlaxoSmithKline

Technical Data for GR 46611

M. Wt	377.49
Formula	C₂₃H₂₇N₃O₂
Storage	Store at RT
CAS Number	185259-85-2
PubChem ID	6160690
InChi Key	LBVZWEWTNUDWNS-YRNVUSSQSA-N
Smiles	O=C(/C=C/C2=CC=C(NC=C3CCN(C)C)C3=C2)NCC1=CC=C(OC)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for GR 46611

References are publications that support the biological activity of the product.

Skingle Stimulation of central 5-HT_1D receptors causes hypothermia in the guinea pig. J.Psychopharmacol.
Clitherow Evolution of a novel series of [(N,N-Dimethylamino)propyl]- and piperazinylbenzanilides as the first selective 5-HT_1D antagonists. J.Med.Chem. 1994 PMID: 8057272

Product Documents for GR 46611

COA

Certificate of Analysis is currently unavailable on-line. Please contact Customer Service.