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Gadolinium chloride

Tocris Bioscience, part of Bio-Techne | Catalog # 4741

Stretch-activated calcium channel blocker; calcium-sensing receptor agonist
Discontinued Product
4741 has been discontinued. View all Other Calcium Channel Compounds products.

Key Product Details

Description

Stretch-activated calcium channel blocker; calcium-sensing receptor agonist

Product Description

Gadolinium chloride is a calcium-sensing receptor (CaSR) agonist; induces NLRP3 inflammasome activation in bone marrow-derived macrophages. Blocks stretch-activated calcium channels; inhibits increase in intracellular calcium ion concentration in hypotonic-stimulated pulmonary artery smooth muscle cells. Has been demonstrated to block TRPML channel currents and other TRP channels.

Product Specifications

Molecular Weight

263.61

Formula

GdCl3

Storage

Desiccate at RT

CAS Number

10138-52-0

PubChem ID

61486

InChI Key

MEANOSLIBWSCIT-UHFFFAOYSA-K

SMILES

Cl[Gd](Cl)Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 26.36 100

Preparing Stock Solutions for Gadolinium chloride

The following data is based on the product molecular weight 263.61

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.79 mL 18.97 mL 37.93 mL
5 mM 0.76 mL 3.79 mL 7.59 mL
10 mM 0.38 mL 1.90 mL 3.79 mL
50 mM 0.08 mL 0.38 mL 0.76 mL

Calculators

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Reconstitution Calculator

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Product Documents for Gadolinium chloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Gadolinium chloride

For research use only

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