G-Protein antagonist peptide

Name: G-Protein antagonist peptide
Brand: Tocris Bioscience
SKU: 1931

Tocris Bioscience, part of Bio-Techne | Catalog # 1931

Citations (13)

COA / SDS

Inhibits G protein activation by GPCRs

Discontinued Product

1931 has been discontinued. View all G Protein (Heterotrimeric) Inhibitors products.

Key Product Details

Description:	Inhibits G protein activation by GPCRs
Alternative Names:	GPAnt-2
Molecular Weight:	1093.27

View Full Technical Details for G-Protein antagonist peptide

Technical Data
Citations

Biological Activity for G-Protein antagonist peptide

G-Protein antagonist peptide is a substance P-related peptide that inhibits binding of G proteins to their receptors. Competitively and reversibly inhibits M₂ muscarinic receptor activation of G_i or G_o and inhibits G_s activation by β-adrenoceptors.

Technical Data for G-Protein antagonist peptide

M. Wt	1093.27
Formula	C₅₇H₆₄N₁₂O₉S
Single Letter Sequence	XQWFWWM (Modifications: X = Glp, Trp-3 = Trp-5 = Trp-6 = D-Trp, Met-7 = C-terminal amide)
Storage	Desiccate at -20°C
CAS Number	143675-79-0
PubChem ID	71308571
InChi Key	WSYRBHQWMXTCHQ-SFIKJRKMSA-N
Smiles	[H]N1[C@@H](CCC1=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCSC)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for G-Protein antagonist peptide

References are publications that support the biological activity of the product.

Mukai G protein antagonists. A novel hydrophobic peptide competes with receptor for G protein binding. J.Biol.Chem. 1992 PMID: 1379592

G-Protein antagonist peptide

Tocris Bioscience, part of Bio-Techne | Catalog # 1931

Key Product Details

Biological Activity for G-Protein antagonist peptide

Technical Data for G-Protein antagonist peptide

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for G-Protein antagonist peptide

Product Documents for G-Protein antagonist peptide

COA

Certificate of Analysis

SDS

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