FR 122047 hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 1507

Cyclooxygenase (COX-1) inhibitor
Discontinued Product
1507 has been discontinued. View all Cyclooxygenase Inhibitors products.

Key Product Details

Description

Cyclooxygenase (COX-1) inhibitor

View all Cyclooxygenase Inhibitors »

Product Description

FR 122047 hydrochloride is a selective cyclooxygenase-1 (COX-1) inhibitor (IC50 values are 0.028 and 65 μM for COX-1 and COX-2 respectively). Antiplatelet, analgesic and anti-inflammatory following oral administration in vivo.

Product Specifications

Molecular Weight

459.99

Formula

C23H25N3O3S.HCl

Storage

Desiccate at +4°C

Purity

≥98% (HPLC)

Chemical Name

1-[[4,5-bis(4-Methoxyphenyl)-2-thiazolyl]carbonyl]-4-methylpiperazine hydrochloride

CAS Number

130717-51-0

PubChem ID

196840

InChI Key

YWMAVHIKOAOSFM-UHFFFAOYSA-N

SMILES

Cl.COC1=CC=C(C=C1)C1=C(N=C(S1)C(=O)N1CCN(C)CC1)C1=CC=C(OC)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 4.6 10

Preparing Stock Solutions for FR 122047 hydrochloride

The following data is based on the product molecular weight 459.99

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.74 mL 108.70 mL 217.40 mL
0.5 mM 4.35 mL 21.74 mL 43.48 mL
1 mM 2.17 mL 10.87 mL 21.74 mL
5 mM 0.43 mL 2.17 mL 4.35 mL

Calculators

Molarity Calculator

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Reconstitution Calculator

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Product Documents for FR 122047 hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for FR 122047 hydrochloride

For research use only

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