Dynamin inhibitory peptide, myristoylated

Name: Dynamin inhibitory peptide, myristoylated
Brand: Tocris Bioscience
SKU: 1775

Tocris Bioscience, part of Bio-Techne | Catalog # 1775

Citations (19)

COA / SDS

Cell-permeable dynamin inhibitor

Discontinued Product

1775 has been discontinued. View all Dynamin Inhibitors products.

Technical Data
Citations & Reviews

Product Description
Product Specifications
Solubility
Calculators
Background References
Product Documents
Specific Notices

Key Product Details

Description

Cell-permeable dynamin inhibitor

View all Dynamin Inhibitors »

Product Description

Dynamin inhibitory peptide, myristoylated is a cell-permeable version of dynamin inhibitory peptide, an inhibitor of the GTPase dynamin that competitively blocks binding of dynamin to amphiphysin, preventing endocytosis. Reduces NMDA receptor internalization.

Control Peptide also available.

Product Specifications

Molecular Weight

1330.64

Formula

C₆₁H₁₀₇N₁₉O₁₄

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

251634-22-7

PubChem ID

90471171

InChI Key

IFTSFTVOMZTNME-ZUSDHBTASA-N

SMILES

[H]N([C@@H](CCC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(N)=O)C(=O)CCCCCCCCCCCCC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Soluble to 1mg/ml in water

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

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Reconstitution Calculator

Background References

References are publications that support the biological activity of the product.

Kittler Constitutive endocytosis of GABA_A receptors by an association with the adaptin AP2 complex modulates inhibitory synaptic currents in hippocampal neurons. J.Neurosci. 2000 PMID: 11050117
Nong Glycine binding primes NMDA receptor internalization. Nature 2003 PMID: 12646920
Grabs The SH3 domain of amphiphysin binds the proline-rich domain of dynamin at a single site that defines a new SH3 binding consensus sequence. J.Biol.Chem. 1997 PMID: 9148966