(±)-Cloprostenol sodium salt
Tocris Bioscience, part of Bio-Techne | Catalog # 2295
Water-soluble PGF2α analog and potent FP receptor agonist
Discontinued Product
2295 has been discontinued.
View all Prostanoid Receptor Agonists products.
Key Product Details
Description
Water-soluble PGF2α analog and potent FP receptor agonist
Product Description
(±)-Cloprostenol sodium salt is a water-soluble prostaglandin F2α (PGF2α) analog; acts as a potent FP receptor agonist (EC50 = 0.84 nM). Potently inhibits differentiation of adipocyte precursor cells. Luteolytic agent in vivo.Product Specifications
Molecular Weight
446.90
Formula
C22H28ClNaO6
Storage
Desiccate at -20°C
Purity
≥98% (HPLC)
Chemical Name
(5Z)-rel-7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-chlorophenoxy)-3-hydroxy-1-butenyl]-3,5-dihydroxycyclopentyl]-5-heptenoic acid monosodium salt
CAS Number
55028-72-3
PubChem ID
17756794
InChI Key
IFEJLMHZNQJGQU-KXXGZHCCSA-M
SMILES
[Na+].O[C@@H](COC1=CC(Cl)=CC=C1)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC([O-])=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 8.94 | 20 |
Preparing Stock Solutions
for (±)-Cloprostenol sodium salt
The following data is based on the product molecular weight 446.90
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.2 mM | 11.19 mL | 55.94 mL | 111.88 mL |
| 1 mM | 2.24 mL | 11.19 mL | 22.38 mL |
| 2 mM | 1.12 mL | 5.59 mL | 11.19 mL |
| 10 mM | 0.22 mL | 1.12 mL | 2.24 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Griffin Pharmacological characterization of an FP prostaglandin receptor on rat vascular smooth muscle cells (A7r5) coupled to phosphoinositide turnover and intracellular calcium mobilization. J.Pharmacol.Exp.Ther. 1998 PMID: 9655886
- Serrero and Lepak Prostaglandin F2α receptor (FP receptor) agonists are potent adipose differentiation inhibitors for primary culture of adipocyte precursors in defined medium. Biochem.Biophys.Res.Comm.
- Dukes Potent luteolytic agents related to prostaglandin F2α. Nature 1974 PMID: 4853720
Product Specific Notices for (±)-Cloprostenol sodium salt
For research use only
Loading...
Loading...