DAU 5884 hydrochloride

Name: DAU 5884 hydrochloride
Brand: Tocris Bioscience
SKU: 2096

Tocris Bioscience, part of Bio-Techne | Catalog # 2096

Citations (7)

COA / SDS

M3 receptor antagonist

Discontinued Product

2096 has been discontinued. View all mAChR M3 Antagonists products.

Key Product Details

Description:	M₃ receptor antagonist
Chemical Name:	8-Methyl-8-azabicyclo-3-endo[3.2.1]oct-3-yl-1,4-dihydro-2-oxo-3(2H)-quinazolinecarboxylic acid ester hydrochloride
Purity:	≥98% (HPLC)
Molecular Weight:	351.83

View Full Technical Details for DAU 5884 hydrochloride

Technical Data
Citations

Biological Activity for DAU 5884 hydrochloride

DAU 5884 hydrochloride is a selective muscarinic M₃ receptor antagonist. In bovine tracheal smooth muscle, inhibits methacholine-dependent effects on cell proliferation and muscle contractility.

Technical Data for DAU 5884 hydrochloride

M. Wt	351.83
Formula	C₁₇H₂₁N₃O₃.HCl
Storage	Desiccate at +4°C
Purity	≥98% (HPLC)
CAS Number	131780-48-8
PubChem ID	16759154
InChi Key	FDERDDSQHZRNGC-LIWIJTDLSA-N
Smiles	Cl.CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)N1CC2=C(NC1=O)C=CC=C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for DAU 5884 hydrochloride

References are publications that support the biological activity of the product.

Gosens Muscarinic M₃ receptor-dependent regulation of airway smooth muscle contractile phenotype. Br.J.Pharmacol. 2004 PMID: 14993104
Roffel Cholinergic contraction of the guinea pig lung strip is mediated by muscarinic M₂-like receptors. Eur.J.Pharmacol. 1993 PMID: 8112384
Gosens Muscarinic M₃-receptors mediate cholinergic synergism of mitogenesis in airway smooth muscle. Am.J.Respir.Cell Mol.Biol. 2003 PMID: 12540494
Doods Characterization of muscarinic receptors in guinea-pig uterus. Eur.J.Pharmacol. 1993 PMID: 8112383

DAU 5884 hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 2096

Key Product Details

Biological Activity for DAU 5884 hydrochloride

Technical Data for DAU 5884 hydrochloride

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for DAU 5884 hydrochloride

Product Documents for DAU 5884 hydrochloride

COA

Certificate of Analysis

SDS

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