CRF (6-33)

Name: CRF (6-33)
Brand: Tocris Bioscience
SKU: 1607

Tocris Bioscience, part of Bio-Techne | Catalog # 1607

COA / SDS

CRF-binding protein inhibitor

Discontinued Product

1607 has been discontinued. View all Additional Non-selective CRF Receptor Products products.

Key Product Details

Description:	CRF-binding protein inhibitor
Alternative Names:	Corticotropin-Releasing Factor (6-33)
Molecular Weight:	3220.68

View Full Technical Details for CRF (6-33)

Technical Data
Citations

Biological Activity for CRF (6-33)

CRF (6-33) is a corticotropin-releasing factor binding protein (CRFBP) inhibitor peptide; displaces CRF from CRFBP. Suppresses body weight gain and increases motor activity in obese rats in vivo.

Licensing Information

Sold with the permission of the SALK Institute

Technical Data for CRF (6-33)

M. Wt	3220.68
Formula	C₁₄₁H₂₃₁N₄₁O₄₃S
Single Letter Sequence	ISLDLTFHLLREVLEMARAEQLAQQAHS
Storage	Desiccate at -20°C
CAS Number	120066-38-8
PubChem ID	16135485
InChi Key	XHHPINGDTRCKNN-QZXFXOMNSA-N
Smiles	[H]N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CO)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

References for CRF (6-33)

References are publications that support the biological activity of the product.

Heinrichs Selective stimulatory actions of corticotropin-releasing factor ligands on correlates of energy balance. Physiol.Behav. 2001 PMID: 11564446
Jahn The binding protein of corticotropin-releasing factor: ligand-binding site and subunit structure. Proc.Natl.Acad.Sci.U.S.A. 2002 PMID: 12215497
Heinrichs Dissociation of arousal-like from anxiogenic-like actions of brain corticotropin-releasing factor receptor ligands in rats. Behav.Brain Res. 2001 PMID: 11287075